HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 116
+	Hs
		349205 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		348586 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		850565 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		349234 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		261626 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		263132 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180783 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		349343 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		349606 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		348604 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		263131 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180782 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		348681 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		348898 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		261663 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		926209 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		263244 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180870 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		1070209 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		180784 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69