Protein: SNAI2
Zinc finger protein SNAI2 (Neural crest transcription factor Slug) (Protein snail homolog 2)

Gene: SNAI2
Organism: Homo sapiens
Interactions: 48
UniProt ID: O43623

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

221786

GSK3B
Glycogen synthase kinase-3 beta

2

4

Small-scale

0.812

High

221784

ZNF76
Zinc finger protein 76

2

20

High-throughput

0.783

High

221790

CSK21
Casein kinase II subunit alpha

2

13

High-throughput

0.783

High

221791

MDM2
E3 ubiquitin-protein ligase Mdm2

3

4

Small-scale

0.670

High

221794

HDAC1
Histone deacetylase 1

3

12

Small-scale

0.640

High

221810

CABP2
Calcium-binding protein 2

2

4

High-throughput

0.606

High

221804

HDAC2
Histone deacetylase 2

2

12

Small-scale

0.584

High

221783

TRI23
E3 ubiquitin-protein ligase TRIM23

1

2

High-throughput

0.573

High

221789

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.561

High

221777

FBSP1
F-box/SPRY domain-containing protein 1

1

6

Small-scale

0.561

High

221803

PIAS4
E3 SUMO-protein ligase PIAS4

1

3

Small-scale

0.561

High

221805

CBP
CREB-binding protein

1

19

Small-scale

0.561

High

221780

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.549

High

221812

FBX28
F-box only protein 28

1

1

Small-scale

0.512

High

221772

PIAS1
E3 SUMO-protein ligase PIAS1

1

3

Small-scale

0.501

High

221773

PIAS2
E3 SUMO-protein ligase PIAS2

1

3

Small-scale

0.501

High

221776

A4
Amyloid-beta precursor protein

1

11

High-throughput

0.501

High

221817

PIAS3
E3 SUMO-protein ligase PIAS3

1

3

Small-scale

0.501

High

221771

KDM1A
Lysine-specific histone demethylase 1A

1

9

Small-scale

0.479

High

221774

RNF8
E3 ubiquitin-protein ligase RNF8

1

17

Small-scale

0.479

High

221775

P53
Cellular tumor antigen p53

1

7

Small-scale

0.479

High

221781

PSA3
Proteasome subunit alpha type-3

1

2

Small-scale

0.479

High

221782

PML
Protein PML

1

20

Small-scale

0.479

High

221785

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

13

Small-scale

0.479

High

221787

PRS4
26S proteasome regulatory subunit 4

1

3

Small-scale

0.479

High

221788

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

7

Small-scale

0.479

High

221792

TF65
Transcription factor p65

1

3

High-throughput

0.479

High

221793

CTBP1
C-terminal-binding protein 1

1

5

Small-scale

0.479

High

221795

CUL4B
Cullin-4B

1

20

Small-scale

0.479

High

221796

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

9

Small-scale

0.479

High

221797

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

5

Small-scale

0.479

High

221799

FBX31
F-box only protein 31

1

1

Small-scale

0.479

High

221800

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

1

Small-scale

0.479

High

221801

U17L2
Ubiquitin carboxyl-terminal hydrolase 17

1

7

Small-scale

0.479

High

221802

SSX7
Protein SSX7

1

3

Small-scale

0.479

High

221806

KAT2B
Histone acetyltransferase KAT2B

1

13

High-throughput

0.479

High

221807

SIN3A
Paired amphipathic helix protein Sin3a

1

1

Small-scale

0.479

High

221808

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

Small-scale

0.479

High

221809

SENP2
Sentrin-specific protease 2

1

3

Small-scale

0.479

High

221813

SENP1
Sentrin-specific protease 1

1

3

Small-scale

0.479

High

221814

ZO2
Tight junction protein 2

1

2

Small-scale

0.479

High

221816

CHIP
E3 ubiquitin-protein ligase CHIP

1

8

Small-scale

0.479

High

210808

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

Small-scale

0.458

High

221779

NELFE
Negative elongation factor E

1

0

High-throughput

0.458

High

221798

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

0

Small-scale

0.458

High

221811

RN146
E3 ubiquitin-protein ligase RNF146

1

0

Small-scale

0.458

High

221815

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.458

High

221778

CADH1
Cadherin-1

1

5

Small-scale

0.437

High


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Last updated: 11Aug2025