HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: RHG31 (Q2M1Z3)
Rho GTPase-activating protein 31 (Cdc42 GTPase-activating protein)
Gene: ARHGAP31

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1444
+	Hs
		64708 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RHG32_HUMAN (1-881): 7.08e-75: 278: 27.77
+	Hs
		349384 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RHG21_HUMAN (6-531): 1.1e-70: 264: 20.32
+	Hs
		1070234 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RHG21_HUMAN (6-531): 1.1e-70: 264: 20.32
+	Hs
		64637 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG32_HUMAN (1-881): 7.08e-75: 278: 27.77
+	Hs
		350234 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG21_HUMAN (6-531): 1.1e-70: 264: 20.32
+	Hs
		895119 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RHG21_HUMAN (6-531): 1.1e-70: 264: 20.32
+	Hs
		49624 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RHG10_HUMAN (37-286): 2.55e-62: 231: 24.11
+	Hs
		349370 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RHG29_HUMAN (10-553): 9.6e-59: 224: 16.36
+	Hs
		349280 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ABR_HUMAN (1-229): 2.38e-56: 214: 30.51
+	Hs
		350325 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG12_HUMAN (1-216): 3.79e-65: 240: 29.68
+	Hs
		348636 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		RHG01_HUMAN (16-221): 1.54e-55: 202: 26.32
+	Hs
		993020 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RHG01_HUMAN (16-221): 1.54e-55: 202: 26.32
+	Hs
		253300 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SRGP2_HUMAN (28-582): 1.39e-52: 204: 15.21
+	Hs
		350113 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG01_HUMAN (16-221): 1.54e-55: 202: 26.32
+	Hs
		895053 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RHG01_HUMAN (16-221): 1.54e-55: 202: 26.32
+	Hs
		914029 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		RHG01_HUMAN (16-221): 1.54e-55: 202: 26.32
+	Hs
		914206 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		RHG18_HUMAN (1-293): 9.99e-53: 199: 18.06
+	Hs
		506558 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		BCR_HUMAN (8-186): 2.88e-18: 93.6: 31.67