HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: FERM2 (Q96AC1)
Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1)
Gene: FERMT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras, PH~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0009898 - cytoplasmic side of plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 680
+	Hs
		349549 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		FERM2_HUMAN (1-680): 0: 1112: 100.00
+	Hs
		348848 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		FERM2_HUMAN (1-680): 0: 1112: 100.00
+	Hs
		1070337 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		FERM2_HUMAN (1-680): 0: 1112: 100.00
+	Hs
		895222 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		FERM2_HUMAN (1-680): 0: 1112: 100.00
+	Hs
		914270 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		FERM2_HUMAN (1-680): 0: 1112: 100.00
+	Hs
		350493 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		FERM1_HUMAN (8-678): 0: 1056: 62.96