Interactor 1: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Interactor 2: PGS2 (P07585)
Decorin (Bone proteoglycan II) (PG-S2) (PG40)
Gene: DCN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 8093006, 9675033, 7798269
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~TGF_beta, LRR_8~TGFb_propeptide
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005796 - Golgi lumen
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 390
Hs

1 359
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024