Interactor 1: GLUC (P01275)
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXM) (OXY); Glucagon; Glucagon-like peptide 1 (GLP-1) (Incretin hormone); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)]
Gene: GCG

Interactor 2: GLP1R (P43220)
Glucagon-like peptide 1 receptor (GLP-1 receptor) (GLP-1-R) (GLP-1R)
Gene: GLP1R

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.738

The method score is based on:

Property Details
Experiments 11116211, 18248821
Identification Methods pull down, unspecified method
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_2~Hormone_2, HRM~Hormone_2
Common GO terms GO:0005886 - plasma membrane
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 180
Hs

1 463
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024