Protein: ITA2
Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)

Gene: ITA2, ITGA2
Organism: Homo sapiens
Interactions: 119
UniProt ID: P17301

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001618 - virus receptor activity
GO:0001666 - response to hypoxia
GO:0002687 - positive regulation of leukocyte migration
GO:0005178 - integrin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

431695

ITB1
Integrin beta-1

4

20

Small-scale

0.883

High

603794

BTNL8
Butyrophilin-like protein 8

3

11

High-throughput

0.861

High

603747

PRTN3
Myeloblastin

1

9

High-throughput

0.691

High

603788

CL12B
C-type lectin domain family 12 member B

1

4

High-throughput

0.691

High

603819

BTNL2
Butyrophilin-like protein 2

1

12

High-throughput

0.691

High

603744

LEG3
Galectin-3

4

20

High-throughput

0.691

High

127272

LEG8
Galectin-8

3

20

High-throughput

0.667

High

603790

ZACN
Ligand-gated cation channel ZACN

3

1

High-throughput

0.667

High

603756

CEAM6
Cell adhesion molecule CEACAM6

1

9

High-throughput

0.665

High

603796

SPA12
Serpin A12

2

5

High-throughput

0.628

High

584665

MCP
Membrane cofactor protein

1

5

Small-scale

0.618

High

603817

MGT4C
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

2

0

High-throughput

0.602

High

480689

LEG1
Galectin-1

2

20

High-throughput

0.601

High

399264

MMP1
Interstitial collagenase

2

12

Small-scale

0.595

High

603743

ITA2
Integrin alpha-2

1

9

Small-scale

0.590

High

375152

RASK
GTPase KRas

2

20

High-throughput

0.584

High

540304

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.584

High

603770

RB11A
Ras-related protein Rab-11A

2

4

High-throughput

0.584

High

603771

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

351655

SG1D1
Secretoglobin family 1D member 1

2

3

High-throughput

0.574

High

603799

TMED6
Transmembrane emp24 domain-containing protein 6

2

2

High-throughput

0.574

High

603745

RAB5A
Ras-related protein Rab-5A

2

6

High-throughput

0.571

High

603793

BRID5
BRICHOS domain-containing protein 5

2

4

High-throughput

0.549

High

277886

SH3L1
Adapter SH3BGRL

2

0

High-throughput

0.547

High

603809

SHRPN
Sharpin

1

7

Small-scale

0.545

High

64343

CDHR4
Cadherin-related family member 4

1

9

High-throughput

0.536

High

351814

BY55
CD160 antigen

1

4

High-throughput

0.536

High

506821

CFC1
Cryptic protein

1

1

High-throughput

0.536

High

563140

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

603752

PDIA3
Protein disulfide-isomerase A3

1

8

Small-scale

0.536

High

603802

ASIC4
Acid-sensing ion channel 4

1

2

High-throughput

0.536

High

603813

PICK1
PRKCA-binding protein

1

4

High-throughput

0.536

High

603820

FBX2
F-box only protein 2

1

15

High-throughput

0.536

High

603786

CAH9
Carbonic anhydrase 9

1

6

High-throughput

0.515

High

421455

A4
Amyloid-beta precursor protein

1

6

Small-scale

0.501

High

430577

FABPH
Fatty acid-binding protein, heart

1

1

Small-scale

0.501

High

465935

CO1A2
Collagen alpha-2(I) chain

1

9

Small-scale

0.501

High

603748

LAMA1
Laminin subunit alpha-1

1

3

Small-scale

0.501

High

389953

ALBU
Albumin

1

1

High-throughput

0.489

High

547962

PSPC
Surfactant protein C

1

5

High-throughput

0.489

High

583436

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

5

High-throughput

0.489

High

603760

DNSL1
Deoxyribonuclease-1-like 1

1

1

High-throughput

0.489

High

603762

EP3B
Epididymal secretory protein E3-beta

1

5

High-throughput

0.489

High

603775

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

3

High-throughput

0.489

High

603785

TAZ
Tafazzin

1

3

High-throughput

0.489

High

603800

CA054
Uncharacterized protein C1orf54

1

5

High-throughput

0.489

High

603803

LCFC1
Sperm-egg fusion protein LLCFC1

1

4

High-throughput

0.489

High

603814

CBLN4
Cerebellin-4

1

20

High-throughput

0.489

High

603746

CD9
CD9 antigen

1

20

High-throughput

0.484

High

126457

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

133637

WASL
Actin nucleation-promoting factor WASL

1

5

Small-scale

0.479

High

217800

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.479

High

340976

DIRA3
GTP-binding protein Di-Ras3

1

8

High-throughput

0.479

High

362724

EGFR
Epidermal growth factor receptor

1

16

Small-scale

0.479

High

374385

RASH
GTPase HRas

1

13

High-throughput

0.479

High

463322

LYN
Tyrosine-protein kinase Lyn

1

6

High-throughput

0.479

High

601167

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

603750

EPHA2
Ephrin type-A receptor 2

1

11

High-throughput

0.479

High

603751

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

603753

UFO
Tyrosine-protein kinase receptor UFO

1

13

Small-scale

0.479

High

603754

CTNB1
Catenin beta-1

1

5

Small-scale

0.479

High

603755

VGFR2
Vascular endothelial growth factor receptor 2

1

6

Small-scale

0.479

High

603757

VHL
von Hippel-Lindau disease tumor suppressor

1

3

Small-scale

0.479

High

603763

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.479

High

603764

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

603766

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

603767

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

603769

ARF6
ADP-ribosylation factor 6

1

7

High-throughput

0.479

High

603772

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

603774

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

603776

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

603779

CUL3
Cullin-3

1

7

High-throughput

0.479

High

603780

CD166
CD166 antigen

1

4

Small-scale

0.479

High

603781

FHL2
Four and a half LIM domains protein 2

1

10

Small-scale

0.479

High

603782

SRC8
Src substrate cortactin

1

2

High-throughput

0.479

High

603784

RAB35
Ras-related protein Rab-35

1

7

High-throughput

0.479

High

603797

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

603804

CIB1
Calcium and integrin-binding protein 1

1

2

Small-scale

0.479

High

603808

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.479

High

603811

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

603822

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

603792

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

349371

TSN15
Tetraspanin-15

1

20

High-throughput

0.445

High

384105

CO1A1
Collagen alpha-1(I) chain

1

8

Small-scale

0.445

High

603768

TSN5
Tetraspanin-5

1

20

High-throughput

0.445

High

603798

TSN14
Tetraspanin-14

1

20

High-throughput

0.445

High

603821

GAB2
GRB2-associated-binding protein 2

1

1

High-throughput

0.445

High

273254

T22D2
TSC22 domain family protein 2

1

4

Small-scale

0.439

High

603759

MSS4
Guanine nucleotide exchange factor MSS4

1

3

Small-scale

0.439

High

603823

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

5

Small-scale

0.439

High

595672

H13
Histone H1.3

1

4

High-throughput

0.437

High

603765

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.437

High

603773

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

603795

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

603816

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

603818

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

369156

OAS1
2'-5'-oligoadenylate synthase 1

1

0

High-throughput

0.426

High

603749

5HT1E
5-hydroxytryptamine receptor 1E

1

0

High-throughput

0.426

High

603758

I12R1
Interleukin-12 receptor subunit beta-1

1

0

High-throughput

0.426

High

603777

CD47
Leukocyte surface antigen CD47

1

0

Small-scale

0.426

High

603787

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.426

High

603812

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.426

High

142275

PEX7
Peroxisomal targeting signal 2 receptor

1

3

High-throughput

0.407

High

170652

CLGN
Calmegin

1

10

High-throughput

0.407

High

273815

CNOT3
CCR4-NOT transcription complex subunit 3

1

4

High-throughput

0.407

High

330037

VENTX
Homeobox protein VENTX

1

1

High-throughput

0.407

High

603789

DB109
Beta-defensin 109B

1

3

High-throughput

0.407

High

603791

KLH22
Kelch-like protein 22

1

7

High-throughput

0.407

High

603815

DDX28
Probable ATP-dependent RNA helicase DDX28

1

7

High-throughput

0.407

High

603805

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.279

Low

603810

UD17
UDP-glucuronosyltransferase 1A7

1

0

High-throughput

0.279

Low

603761

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.249

Low

603807

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.249

Low

603778

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

603783

NAA30
N-alpha-acetyltransferase 30

1

0

High-throughput

0.232

Low

603801

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.232

Low

603806

OSB11
Oxysterol-binding protein-related protein 11

1

0

High-throughput

0.232

Low

603824

TX264
Testis-expressed protein 264

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025