HitPredict

Interactor 1: IL1B (P01584)
Interleukin-1 beta (IL-1 beta) (Catabolin)
Gene: IL1B

Interactor 2: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19122653
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006954 - inflammatory response GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 269 Hs			1 619
+	Hs
		981763 I36RA_HUMAN (121-265): 1.59e-55: 177: 28.67		REL_HUMAN (1-619): 0: 692: 100.00
+	Mm
		499365 IL1B_MOUSE (1-269): 1.8e-124: 356: 67.53		TF65_MOUSE (2-576): 1.99e-167: 490: 38.89
+	Hs
		352999 IL1B_HUMAN (1-269): 1.39e-131: 374: 100.00		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		352984 IL1B_HUMAN (1-269): 1.39e-131: 374: 100.00		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		352997 IL1B_HUMAN (1-269): 1.39e-131: 374: 100.00		RELB_HUMAN (2-479): 1.52e-143: 430: 35.04
+	Hs
		352964 IL1A_HUMAN (1-262): 3.95e-87: 262: 23.32		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		577487 IL1RA_HUMAN (90-265): 1.55e-49: 163: 25.68		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89