HitPredict

Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: PAPP1 (Q13219)
Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A)
Gene: PAPPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15174051
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 399 Hs			1 1627
+	Hs
		353933 IGHM_HUMAN (1-358): 2.62e-22: 100: 19.90		PAPP1_HUMAN (1-1627): 0: 2176: 100.00
+	Hs
		353612 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		F13B_HUMAN (1109-1595): 5.56e-33: 139: 15.88
+	Hs
		353692 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		FRAS1_HUMAN (1207-1607): 4.93e-16: 86.8: 14.06
+	Hs
		354026 IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85		F13B_HUMAN (1109-1595): 5.56e-33: 139: 15.88
+	Hs
		353488 IGKC_HUMAN (229-321): 1.52e-09: 57: 29.47		F13B_HUMAN (1109-1595): 5.56e-33: 139: 15.88
+	Hs
		980481 PXDN_HUMAN (2-154): 1.82e-11: 68.1: 12.26		NOTC2_HUMAN (1353-1622): 5.92e-10: 66.7: 11.91