HitPredict

Interactor 1: DRB1 (P01911)
HLA class II histocompatibility antigen, DRB1 beta chain (Human leukocyte antigen DRB1) (HLA-DRB1)
Gene: HLA-DRB1

Interactor 2: DQB1 (P01920)
HLA class II histocompatibility antigen, DQ beta 1 chain (MHC class II antigen DQB1)
Gene: HLA-DQB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 33961781
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_II_beta, MHC_II_beta~MHC_II_beta
Common GO terms GO:0000139 - Golgi membrane
GO:0002503 - peptide antigen assembly with MHC class II protein complex
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0006955 - immune response
and 17 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 266
Hs

1 261
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024