HitPredict

Interactor 1: H2B (P02283)
Histone H2B
Gene: H2B, His2B;

Interactor 2: TIP60 (Q960X4)
Histone acetyltransferase Tip60 (EC 2.3.1.48)
Gene: TIP60

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15528408
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 123 Dm			1 541
+	Mm
		1145470 H2B2B_MOUSE (3-123): 3.44e-49: 154: 81.30		KAT5_MOUSE (23-541): 0: 707: 58.38
+	Hs
		707704 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KAT5_HUMAN (23-541): 0: 707: 58.38
+	Hs
		918578 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		KAT5_HUMAN (23-541): 0: 707: 58.38
+	Hs
		1231219 H2B3B_HUMAN (3-123): 1.14e-46: 148: 81.30		KAT5_HUMAN (23-541): 0: 707: 58.38
+	Hs
		1273427 H2B1A_HUMAN (3-123): 2.12e-43: 139: 78.57		KAT5_HUMAN (23-541): 0: 707: 58.38
+	Hs
		1087406 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		KAT8_HUMAN (128-533): 2.58e-156: 455: 39.30
+	Hs
		918694 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		KAT8_HUMAN (128-533): 2.58e-156: 455: 39.30
+	Hs
		309661 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		KAT7_HUMAN (260-533): 5.34e-149: 442: 53.79
+	Hs
		309686 H2B1C_HUMAN (3-123): 1.51e-48: 153: 81.30		KAT7_HUMAN (260-533): 5.34e-149: 442: 53.79
+	Hs
		309707 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		KAT7_HUMAN (260-533): 5.34e-149: 442: 53.79
+	Hs
		1129832 H2B2F_HUMAN (3-123): 3.44e-49: 154: 81.30		KAT6A_HUMAN (84-533): 2.22e-137: 440: 35.64
+	Hs
		617965 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		KAT6A_HUMAN (84-533): 2.22e-137: 440: 35.64
+	Hs
		1087309 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		KAT6A_HUMAN (84-533): 2.22e-137: 440: 35.64
+	Hs
		1264460 H2B1H_HUMAN (3-123): 5.28e-49: 154: 81.30		KAT6B_HUMAN (203-533): 4.76e-133: 428: 42.86
+	Hs
		617961 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		KAT6B_HUMAN (203-533): 4.76e-133: 428: 42.86
+	Hs
		1087295 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		KAT6B_HUMAN (203-533): 4.76e-133: 428: 42.86
+	Sc
		355855 H2B2_YEAST (3-122): 1.26e-41: 135: 68.33		SAS3_YEAST (247-533): 1.74e-118: 370: 42.37
+	Sc
		355435 H2B1_YEAST (3-122): 1.66e-40: 133: 68.33		SAS3_YEAST (247-533): 1.74e-118: 370: 42.37
+	Sc
		356037 H2B2_YEAST (3-122): 1.26e-41: 135: 68.33		ESA1_YEAST (3-85): 1.21e-11: 68.7: 33.33
+	Sc
		355677 H2B1_YEAST (3-122): 1.66e-40: 133: 68.33		ESA1_YEAST (3-85): 1.21e-11: 68.7: 33.33