HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: CHD1 (P32657)
Chromo domain-containing protein 1 (EC 3.6.4.-) (ATP-dependent helicase CHD1)
Gene: CHD1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.970

Property	Details
Experiments	11805826, 37968396, 22199229, 16429126, 27174939, 29019976, 30005873, 31636125, 21179020
Identification Methods	tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C, CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 1468
+	Hs
		917965 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD8_HUMAN (2-1377): 0: 934: 26.15
+	Hs
		917364 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD9_HUMAN (20-1378): 0: 921: 26.06
+	Sp
		144535 H4_SCHPO (18-103): 2.79e-41: 133: 90.70		HRP3_SCHPO (7-1463): 0: 914: 46.24
+	Hs
		151483 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD2_HUMAN (5-1468): 0: 876: 31.11
+	Hs
		229352 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SMCA5_HUMAN (245-1274): 0: 777: 26.33
+	Hs
		846914 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SMCA4_HUMAN (3-1106): 0: 755: 23.19
+	Sc
		356774 H4_YEAST (1-103): 5.28e-47: 147: 100.00		ISW2_YEAST (364-933): 1.41e-126: 424: 42.98
+	Dm
		950383 H4_DROME (18-103): 2.42e-41: 133: 90.70		ISWI_DROME (363-927): 1.74e-130: 432: 42.88
+	Hs
		918062 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD7_HUMAN (923-1410): 1.58e-18: 94.7: 11.27
+	Hs
		917182 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD3_HUMAN (959-1364): 1.33e-13: 78.5: 9.57
+	Hs
		917277 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD4_HUMAN (959-1353): 6.6e-11: 69.7: 12.19
+	Hs
		917635 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CHD6_HUMAN (922-1380): 3.8e-10: 67.4: 11.57