HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: RSC1 (P53236)
Chromatin structure-remodeling complex subunit RSC1 (RSC complex subunit RSC1) (Remodel the structure of chromatin complex subunit 1)
Gene: RSC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.80	0.740

Property	Details
Experiments	17049045, 21749977, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	BAH~CENP-T_C
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Sc			1 928
+	Sc
		356741 H4_YEAST (1-103): 5.28e-47: 147: 100.00		RSC2_YEAST (8-816): 0: 578: 46.49
+	Mm
		918262 H4_MOUSE (18-103): 1.92e-41: 133: 90.70		BRDT_MOUSE (1-478): 6.51e-79: 278: 15.49
+	Hs
		917299 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD3_HUMAN (4-345): 9.76e-74: 259: 17.51
+	Zm
		19319 A0A1D6IAU4_MAIZE (18-103): 9.75e-45: 142: 89.54		A0A1D6HCG5_MAIZE (11-268): 2.62e-29: 126: 16.35
+	Hs
		846914 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SMCA4_HUMAN (3-107): 1.76e-28: 126: 33.33
+	Hs
		631388 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD2_HUMAN (3-234): 1.91e-28: 124: 13.47
+	Hs
		917170 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		EP300_HUMAN (5-120): 6.74e-26: 117: 23.33
+	Hs
		244235 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD4_HUMAN (3-160): 3.4e-24: 112: 18.52
+	Sc
		356398 H4_YEAST (1-103): 5.28e-47: 147: 100.00		BDF1_YEAST (187-532): 2.06e-18: 92.4: 11.54
+	Sc
		356752 H4_YEAST (1-103): 5.28e-47: 147: 100.00		BDF2_YEAST (247-368): 3.1e-18: 91.6: 15.32
+	Sc
		356248 H4_YEAST (1-103): 5.28e-47: 147: 100.00		SNF2_YEAST (11-108): 7.23e-18: 91.4: 31.00
+	Hs
		917466 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRWD3_HUMAN (5-238): 1.86e-21: 103: 16.17
+	Hs
		917517 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		PB1_HUMAN (190-723): 8.96e-20: 97.8: 14.31
+	Dm
		950405 H4_DROME (18-103): 2.42e-41: 133: 90.70		Q9VCG6_DROME (195-373): 1.46e-18: 92.3: 17.49
+	Hs
		917576 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TAF1L_HUMAN (13-115): 5.66e-18: 92: 21.91
+	Hs
		600119 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TAF1_HUMAN (13-115): 8.59e-18: 91.2: 21.91
+	Sc
		356344 H4_YEAST (1-103): 5.28e-47: 147: 100.00		STH1_YEAST (235-344): 5.88e-11: 68.7: 24.55
+	Sc
		356667 H4_YEAST (1-103): 5.28e-47: 147: 100.00		RSC4_YEAST (26-120): 9.35e-11: 67.5: 26.80
+	Sc
		356682 H4_YEAST (1-103): 5.28e-47: 147: 100.00		GCN5_YEAST (35-109): 1.3e-10: 66.7: 35.07
+	Hs
		170320 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TIF1A_HUMAN (45-123): 2.48e-11: 69.8: 39.76