HitPredict

Interactor 1: PLK4 (O97143)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase SAK)
Gene: SAK

Interactor 2: Q9VH81 (Q9VH81)
protein-serine/threonine phosphatase (EC 3.1.3.16)
Gene: PpD3

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25294943
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 769 Dm			1 520
+	Hs
		692035 MARK3_HUMAN (3-655): 1.8e-156: 475: 20.00		PP2AB_HUMAN (205-503): 8.14e-165: 470: 38.33
+	Hs
		136071 PLK4_HUMAN (8-287): 3.37e-122: 391: 57.86		PP2AB_HUMAN (205-503): 8.14e-165: 470: 38.33
+	Hs
		136073 PLK4_HUMAN (8-287): 3.37e-122: 391: 57.86		PP2AA_HUMAN (205-503): 8.98e-164: 468: 38.33
+	Hs
		919868 PLK1_HUMAN (19-266): 7.4e-56: 204: 41.04		PP2AB_HUMAN (205-503): 8.14e-165: 470: 38.33
+	Hs
		919879 PLK1_HUMAN (19-266): 7.4e-56: 204: 41.04		PP2AA_HUMAN (205-503): 8.98e-164: 468: 38.33
+	Hs
		919849 PLK1_HUMAN (19-266): 7.4e-56: 204: 41.04		PP4C_HUMAN (210-510): 1.57e-162: 464: 38.44
+	Hs
		919863 PLK1_HUMAN (19-266): 7.4e-56: 204: 41.04		PP1B_HUMAN (218-515): 3.73e-162: 464: 36.79
+	Hs
		786465 PLK1_HUMAN (19-266): 7.4e-56: 204: 41.04		PP1G_HUMAN (220-505): 3.45e-161: 462: 38.68
+	Hs
		919862 PLK1_HUMAN (19-266): 7.4e-56: 204: 41.04		PP1A_HUMAN (220-503): 2.09e-161: 462: 38.95
+	Hs
		170058 AURKA_HUMAN (11-267): 2.55e-54: 194: 38.91		PP2AB_HUMAN (205-503): 8.14e-165: 470: 38.33
+	Hs
		170070 AURKA_HUMAN (11-267): 2.55e-54: 194: 38.91		PP2AA_HUMAN (205-503): 8.98e-164: 468: 38.33
+	Hs
		994336 AURKB_HUMAN (10-267): 4.1e-54: 192: 39.92		PP2AA_HUMAN (205-503): 8.98e-164: 468: 38.33
+	Hs
		170050 AURKA_HUMAN (11-267): 2.55e-54: 194: 38.91		PP1B_HUMAN (218-515): 3.73e-162: 464: 36.79
+	Hs
		169985 AURKA_HUMAN (11-267): 2.55e-54: 194: 38.91		PP1G_HUMAN (220-505): 3.45e-161: 462: 38.68
+	Hs
		170049 AURKA_HUMAN (11-267): 2.55e-54: 194: 38.91		PP1A_HUMAN (220-503): 2.09e-161: 462: 38.95
+	Hs
		786775 AURKB_HUMAN (10-267): 4.1e-54: 192: 39.92		PP1G_HUMAN (220-505): 3.45e-161: 462: 38.68
+	Hs
		967909 AURKB_HUMAN (10-267): 4.1e-54: 192: 39.92		PP1A_HUMAN (220-503): 2.09e-161: 462: 38.95