HitPredict

Interactor 1: RPAC1 (O15160)
DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)
Gene: POLR1C

Interactor 2: GPN3 (Q9UHW5)
GPN-loop GTPase 3 (ATP-binding domain 1 family member C)
Gene: GPN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.50	0.638

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 284
+	Hs
		169961 RPAC1_HUMAN (1-346): 6.24e-179: 501: 100.00		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40
+	Hs
		583622 RPB3_HUMAN (45-346): 4.01e-105: 311: 26.38		GPN3_HUMAN (1-284): 1.23e-155: 437: 100.00
+	Hs
		583586 RPB3_HUMAN (45-346): 4.01e-105: 311: 26.38		GPN2_HUMAN (4-254): 1.73e-132: 379: 42.13
+	Sc
		429734 RPAC1_YEAST (10-338): 1.98e-143: 410: 44.88		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34
+	Sc
		558272 RPB3_YEAST (46-346): 5.64e-100: 299: 25.74		GPN3_YEAST (1-268): 5.79e-122: 351: 43.17
+	Sc
		558300 RPB3_YEAST (46-346): 5.64e-100: 299: 25.74		GPN2_YEAST (3-254): 8.37e-105: 310: 34.35
+	Hs
		583591 RPB3_HUMAN (45-346): 4.01e-105: 311: 26.38		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40
+	Sc
		558136 RPB3_YEAST (46-346): 5.64e-100: 299: 25.74		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34