Interactor 1: CRYAA (P02470)
Alpha-crystallin A chain [Cleaved into: Alpha-crystallin A(1-172); Alpha-crystallin A(1-168)]
Gene: CRYAA

Interactor 2: CRYAB (P02510)
Alpha-crystallin B chain (Alpha(B)-crystallin)
Gene: CRYAB

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.721

The method score is based on:

Property Details
Experiments 19651604
Identification Methods cosedimentation in solution, transmission electron microscopy, molecular sieving, dynamic light scattering
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Crystallin~Crystallin, Crystallin~HSP20, HSP20~HSP20
Common GO terms GO:0005212 - structural constituent of eye lens
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0009408 - response to heat
GO:0043066 - negative regulation of apoptotic process
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 173
Bt

1 175
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024