HitPredict

Interactor 1: CRYAB (P02511)
Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Heat shock protein family B member 5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component)
Gene: CRYAB

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

The method score is based on:

Property	Details
Experiments	19343786, 19799611
Identification Methods	affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol and 7 others more... GO:0030308 - negative regulation of cell growth GO:0032991 - protein-containing complex GO:0043066 - negative regulation of apoptotic process GO:0045892 - negative regulation of DNA-templated transcription GO:0050821 - protein stabilization GO:0071480 - cellular response to gamma radiation GO:2000378 - negative regulation of reactive oxygen species metabolic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	175
Hs

1	393

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024