HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: DDX24 (Q9GZR7)
ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24)
Gene: DDX24

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	24623722
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 664 Hs			1 859
+	Hs
		531628 K2C5_HUMAN (24-390): 2.24e-117: 364: 25.95		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		133866 K2C5_HUMAN (24-390): 2.24e-117: 364: 25.95		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		133822 K2C6A_HUMAN (23-407): 5.26e-116: 360: 23.71		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		133831 K2C6B_HUMAN (24-407): 5.03e-115: 357: 23.51		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		943694 KRT85_HUMAN (25-387): 4.71e-48: 178: 24.93		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		318882 K2C75_HUMAN (23-390): 1.2e-45: 172: 23.85		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		1326341 KRT82_HUMAN (23-387): 1.44e-44: 168: 23.84		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		133823 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		1055195 K1H2_HUMAN (30-387): 6.02e-43: 162: 23.18		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		359643 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		DDX5_HUMAN (232-774): 1.14e-121: 382: 19.89
+	Hs
		1270305 KRT35_HUMAN (30-387): 1.7e-41: 158: 24.58		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		443791 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Mm
		821712 LMNA_MOUSE (1-664): 1.23e-70: 243: 94.90		DDX3Y_MOUSE (159-723): 4.56e-116: 369: 18.94
+	Dr
		71414 B3DKC5_DANRE (9-597): 8e-53: 194: 65.08		E7F1G8_DANRE (199-720): 3.45e-135: 413: 23.81
+	Hs
		595496 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		DDX49_HUMAN (335-829): 3.53e-136: 416: 26.79
+	Dr
		71465 B3DKC5_DANRE (9-597): 8e-53: 194: 65.08		DDX46_DANRE (72-849): 9.69e-127: 407: 16.05
+	Hs
		1326340 KRT84_HUMAN (233-645): 2.05e-11: 69.1: 13.60		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		360468 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		360112 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		DDX42_HUMAN (4-267): 1.44e-16: 86.7: 14.61
+	Hs
		595438 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69