HitPredict

Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19738201
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CH~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2477 Hs			1 2725
+	Hs
		362811 FINC_HUMAN (1-2477): 0: 1538: 100.00		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		261173 FINC_HUMAN (1-2477): 0: 1538: 100.00		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		211454 FINC_HUMAN (1-2477): 0: 1538: 100.00		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		363087 FINC_HUMAN (1-2477): 0: 1538: 100.00		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		363077 FINC_HUMAN (1-2477): 0: 1538: 100.00		PGBM_HUMAN (1306-2725): 4.84e-73: 276: 11.87
+	Hs
		362655 FINC_HUMAN (1-2477): 0: 1538: 100.00		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		363240 FINC_HUMAN (1-2477): 0: 1538: 100.00		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78
+	Hs
		234453 DSCAM_HUMAN (1269-2389): 1.73e-81: 302: 9.48		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		234468 DSCAM_HUMAN (1269-2389): 1.73e-81: 302: 9.48		ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30
+	Hs
		211436 DSCAM_HUMAN (1269-2389): 1.73e-81: 302: 9.48		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		234502 DSCAM_HUMAN (1269-2389): 1.73e-81: 302: 9.48		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		234551 DSCAM_HUMAN (1269-2389): 1.73e-81: 302: 9.48		SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65
+	Hs
		725715 TENN_HUMAN (581-1107): 2.67e-65: 247: 23.15		ACTN2_HUMAN (2-387): 2.32e-122: 412: 26.00
+	Ce
		1095237 Q9UB29_CAEEL (574-1918): 1.38e-77: 290: 16.57		Q23158_CAEEL (16-315): 1.14e-104: 361: 28.93
+	Ce
		1095236 Q9UB28_CAEEL (574-1918): 6.27e-77: 288: 16.57		Q23158_CAEEL (16-315): 1.14e-104: 361: 28.93
+	Hs
		362826 TENA_HUMAN (1508-2390): 2.36e-71: 269: 17.23		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Dm
		574825 TITIN_DROME (1910-2401): 6.36e-13: 77.5: 10.47		ACTN_DROME (1-386): 1.84e-105: 364: 25.90
+	Hs
		363093 CO7A1_HUMAN (1981-2282): 5e-21: 104: 19.87		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		362710 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		362773 MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83