Protein: CTR4
Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4)

Gene: CTR4, SLC7A4
Organism: Homo sapiens
Interactions: 107
UniProt ID: O43246

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006865 - amino acid transport
GO:0015171 - amino acid transmembrane transporter activity
GO:0015174 - basic amino acid transmembrane transporter activity
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

211102

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

17

High-throughput

0.576

High

211138

CD276
CD276 antigen

1

6

High-throughput

0.575

High

211156

S7A14
Solute carrier family 7 member 14

1

15

High-throughput

0.575

High

48447

ESYT2
Extended synaptotagmin-2

1

4

High-throughput

0.445

High

50444

HACL2
2-hydroxyacyl-CoA lyase 2

1

5

High-throughput

0.445

High

178869

SCAM2
Secretory carrier-associated membrane protein 2

1

5

High-throughput

0.445

High

211096

EXTL3
Exostosin-like 3

1

3

High-throughput

0.445

High

211097

ATP9A
Probable phospholipid-transporting ATPase IIA

1

7

High-throughput

0.445

High

211098

ATRN
Attractin

1

8

High-throughput

0.445

High

211099

PRAF3
PRA1 family protein 3

1

2

High-throughput

0.445

High

211100

RTN3
Reticulon-3

1

5

High-throughput

0.445

High

211101

RASN
GTPase NRas

1

20

High-throughput

0.445

High

211103

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

4

High-throughput

0.445

High

211104

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

2

High-throughput

0.445

High

211105

FYN
Tyrosine-protein kinase Fyn

1

9

High-throughput

0.445

High

211106

YES
Tyrosine-protein kinase Yes

1

10

High-throughput

0.445

High

211107

MDR1
ATP-dependent translocase ABCB1

1

4

High-throughput

0.445

High

211108

SRPRA
Signal recognition particle receptor subunit alpha

1

3

High-throughput

0.445

High

211109

MPRI
Cation-independent mannose-6-phosphate receptor

1

4

High-throughput

0.445

High

211110

NCAM1
Neural cell adhesion molecule 1

1

2

High-throughput

0.445

High

211111

NCPR
NADPH--cytochrome P450 reductase

1

4

High-throughput

0.445

High

211115

TNR6
Tumor necrosis factor receptor superfamily member 6

1

5

High-throughput

0.445

High

211116

STOM
Stomatin

1

2

High-throughput

0.445

High

211118

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

2

High-throughput

0.445

High

211120

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.445

High

211121

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

2

High-throughput

0.445

High

211123

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

1

High-throughput

0.445

High

211124

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

4

High-throughput

0.445

High

211126

RAB14
Ras-related protein Rab-14

1

13

High-throughput

0.445

High

211127

RRAS2
Ras-related protein R-Ras2

1

17

High-throughput

0.445

High

211128

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

2

High-throughput

0.445

High

211129

AT2C1
Calcium-transporting ATPase type 2C member 1

1

4

High-throughput

0.445

High

211130

TMED1
Transmembrane emp24 domain-containing protein 1

1

17

High-throughput

0.445

High

211131

MLEC
Malectin

1

1

High-throughput

0.445

High

211133

DHC24
Delta(24)-sterol reductase

1

4

High-throughput

0.445

High

211135

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

2

High-throughput

0.445

High

211139

RETST
All-trans-retinol 13,14-reductase

1

5

High-throughput

0.445

High

211141

QSOX2
Sulfhydryl oxidase 2

1

3

High-throughput

0.445

High

211145

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

1

High-throughput

0.445

High

211147

ZDH13
Palmitoyltransferase ZDHHC13

1

6

High-throughput

0.445

High

211149

LMTK2
Serine/threonine-protein kinase LMTK2

1

19

High-throughput

0.445

High

211150

K2013
Uncharacterized protein KIAA2013

1

2

High-throughput

0.445

High

211151

GHDC
GH3 domain-containing protein

1

1

High-throughput

0.445

High

211152

AT11C
Phospholipid-transporting ATPase IG

1

7

High-throughput

0.445

High

211155

RAI3
Retinoic acid-induced protein 3

1

2

High-throughput

0.445

High

211157

PO210
Nuclear pore membrane glycoprotein 210

1

2

High-throughput

0.445

High

211161

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

5

High-throughput

0.445

High

211164

CERS2
Ceramide synthase 2

1

8

High-throughput

0.445

High

211165

TM41A
Transmembrane protein 41A

1

3

High-throughput

0.445

High

211166

DNJC1
DnaJ homolog subfamily C member 1

1

7

High-throughput

0.445

High

211167

SORT
Sortilin

1

1

High-throughput

0.445

High

211168

CHP1
Calcineurin B homologous protein 1

1

4

High-throughput

0.445

High

211170

ADPGK
ADP-dependent glucokinase

1

3

High-throughput

0.445

High

211171

ESYT1
Extended synaptotagmin-1

1

5

High-throughput

0.445

High

211172

ALG1
Chitobiosyldiphosphodolichol beta-mannosyltransferase

1

2

High-throughput

0.445

High

211173

TMM43
Transmembrane protein 43

1

4

High-throughput

0.445

High

211176

FUT8
Alpha-(1,6)-fucosyltransferase

1

1

High-throughput

0.445

High

211177

LNP
Endoplasmic reticulum junction formation protein lunapark

1

4

High-throughput

0.445

High

211178

DERL2
Derlin-2

1

3

High-throughput

0.445

High

211184

TM9S3
Transmembrane 9 superfamily member 3

1

7

High-throughput

0.445

High

211185

RTN4
Reticulon-4

1

5

High-throughput

0.445

High

211186

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

7

High-throughput

0.445

High

211188

CC50A
Cell cycle control protein 50A

1

2

High-throughput

0.445

High

211191

CEIP2
Cell surface hyaluronidase CEMIP2

1

3

High-throughput

0.445

High

211192

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

3

High-throughput

0.445

High

211193

ABCG2
Broad substrate specificity ATP-binding cassette transporter ABCG2

1

6

High-throughput

0.445

High

211194

AT11B
Phospholipid-transporting ATPase IF

1

7

High-throughput

0.445

High

211195

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

2

High-throughput

0.445

High

211113

MPRD
Cation-dependent mannose-6-phosphate receptor

1

0

High-throughput

0.426

High

211114

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.426

High

211119

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.426

High

211136

AGK
Acylglycerol kinase, mitochondrial

1

0

High-throughput

0.426

High

211137

SFT2C
Vesicle transport protein SFT2C

1

0

High-throughput

0.426

High

211142

TMPPE
Transmembrane protein with metallophosphoesterase domain

1

0

High-throughput

0.426

High

211162

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.426

High

211179

T126A
Transmembrane protein 126A

1

0

High-throughput

0.426

High

211182

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.426

High

211189

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.426

High

163526

TPP1
Tripeptidyl-peptidase 1

1

1

High-throughput

0.407

High

165485

SCAM3
Secretory carrier-associated membrane protein 3

1

5

High-throughput

0.407

High

168155

HAT1
Histone acetyltransferase type B catalytic subunit

1

1

High-throughput

0.407

High

211117

TPP2
Tripeptidyl-peptidase 2

1

3

High-throughput

0.407

High

211122

TXTP
Tricarboxylate transport protein, mitochondrial

1

2

High-throughput

0.407

High

211125

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

4

High-throughput

0.407

High

211134

RTN1
Reticulon-1

1

5

High-throughput

0.407

High

211140

TMT1B
Thiol S-methyltransferase TMT1B

1

2

High-throughput

0.407

High

211143

MAVS
Mitochondrial antiviral-signaling protein

1

3

High-throughput

0.407

High

211144

RETR3
Reticulophagy regulator 3

1

1

High-throughput

0.407

High

211146

STX12
Syntaxin-12

1

11

High-throughput

0.407

High

211148

ZDH17
Palmitoyltransferase ZDHHC17

1

9

High-throughput

0.407

High

211153

XXLT1
Xyloside xylosyltransferase 1

1

1

High-throughput

0.407

High

211158

THEM6
Protein THEM6

1

1

High-throughput

0.407

High

211159

SCFD1
Sec1 family domain-containing protein 1

1

9

High-throughput

0.407

High

211160

SNX19
Sorting nexin-19

1

5

High-throughput

0.407

High

211169

PGAP4
GPI-N-acetylgalactosamine transferase PGAP4

1

3

High-throughput

0.407

High

211174

TIM21
Mitochondrial import inner membrane translocase subunit Tim21

1

2

High-throughput

0.407

High

211175

HIG2A
HIG1 domain family member 2A, mitochondrial

1

1

High-throughput

0.407

High

211180

5NT3A
Cytosolic 5'-nucleotidase 3A

1

1

High-throughput

0.407

High

211181

SNX25
Sorting nexin-25

1

5

High-throughput

0.407

High

211183

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

1

High-throughput

0.407

High

211187

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

3

High-throughput

0.407

High

211190

PCYOX
Prenylcysteine oxidase 1

1

1

High-throughput

0.407

High

81661

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

1

0

High-throughput

0.232

Low

211112

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

1

0

High-throughput

0.232

Low

211132

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

High-throughput

0.232

Low

211154

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.232

Low

211163

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025