HitPredict

Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: FBN3 (Q75N90)
Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide]
Gene: FBN3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	25034023
Identification Methods	solid phase assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	EGF_3~fn3, EGF_CA~fn3
Common GO terms	GO:0005201 - extracellular matrix structural constituent GO:0005576 - extracellular region GO:0031012 - extracellular matrix
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2477 Hs			1 2809
+	Hs
		362882 FINC_HUMAN (1-2477): 0: 1538: 100.00		FBN2_HUMAN (12-1277): 8.45e-82: 304: 24.38
+	Hs
		362826 FINC_HUMAN (1-2477): 0: 1538: 100.00		TENA_HUMAN (542-1109): 2.4e-43: 177: 13.71
+	Hs
		362881 FINC_HUMAN (1-2477): 0: 1538: 100.00		FBN1_HUMAN (2-763): 9.87e-36: 152: 19.78
+	Hs
		363076 FINC_HUMAN (1-2477): 0: 1538: 100.00		FBLN2_HUMAN (1361-1789): 3.73e-21: 104: 27.68
+	Hs
		362819 FINC_HUMAN (1-2477): 0: 1538: 100.00		FBLN1_HUMAN (401-556): 3.2e-17: 90.5: 37.65
+	Hs
		363151 FINC_HUMAN (1-2477): 0: 1538: 100.00		LTBP1_HUMAN (10-534): 1.06e-11: 73.2: 14.29
+	Hs
		957263 PGBM_HUMAN (122-745): 3.46e-09: 65.1: 9.56		FBLN2_HUMAN (1361-1789): 3.73e-21: 104: 27.68
+	Hs
		439247 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		SCUB3_HUMAN (407-538): 1.76e-09: 65.9: 37.31
+	Hs
		540435 MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31		SCUB3_HUMAN (407-538): 1.76e-09: 65.9: 37.31
+	Hs
		957542 PGBM_HUMAN (122-745): 3.46e-09: 65.1: 9.56		LTBP2_HUMAN (5-764): 6.82e-14: 80.5: 15.58