HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: STIM1 (Q13586)
Stromal interaction molecule 1
Gene: STIM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 685
+	Hs
		410823 ERBB2_HUMAN (5-1203): 0: 1119: 48.38		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		641589 ERBB3_HUMAN (1-1205): 0: 1102: 41.39		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		463957 RET_HUMAN (412-1058): 7.91e-132: 433: 23.02		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		710828 EPHB2_HUMAN (642-1067): 2.14e-123: 408: 28.22		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		179608 MUSK_HUMAN (477-976): 2.77e-122: 401: 22.08		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		710227 EPHA2_HUMAN (665-1016): 2.96e-113: 379: 32.79		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		465513 IGF1R_HUMAN (438-1062): 5.28e-109: 375: 20.53		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		464069 RET_HUMAN (412-1058): 7.91e-132: 433: 23.02		STIM2_HUMAN (49-643): 0: 826: 51.93
+	Hs
		710534 EPHA2_HUMAN (665-1016): 2.96e-113: 379: 32.79		STIM2_HUMAN (49-643): 0: 826: 51.93
+	Hs
		465676 IGF1R_HUMAN (438-1062): 5.28e-109: 375: 20.53		STIM2_HUMAN (49-643): 0: 826: 51.93
+	Hs
		439726 INSR_HUMAN (336-637): 2.63e-27: 122: 21.64		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		572923 INSRR_HUMAN (336-656): 1.4e-24: 113: 20.62		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		439867 INSR_HUMAN (336-637): 2.63e-27: 122: 21.64		STIM2_HUMAN (49-643): 0: 826: 51.93