HitPredict

Interactor 1: PLF4 (P02776)
Platelet factor 4 (PF-4) (C-X-C motif chemokine 4) (Iroplact) (Oncostatin-A) [Cleaved into: Platelet factor 4, short form (Endothelial cell growth inhibitor)]
Gene: PF4

Interactor 2: CCL20 (P78556)
C-C motif chemokine 20 (Beta-chemokine exodus-1) (CC chemokine LARC) (Liver and activation-regulated chemokine) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Small-inducible cytokine A20) [Cleaved into: CCL20(1-67); CCL20(1-64); CCL20(2-70)]
Gene: CCL20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.716

The method score is based on:

Property Details
Experiments 28381538
Identification Methods pull down, surface plasmon resonance, filter binding
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006954 - inflammatory response
GO:0008009 - chemokine activity
GO:0030593 - neutrophil chemotaxis
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 101
Hs

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Last updated: 15 Jul 2024