HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MAGA4 (P43358)
Melanoma-associated antigen 4 (Cancer/testis antigen 1.4) (CT1.4) (MAGE-4 antigen) (MAGE-41 antigen) (MAGE-X2 antigen)
Gene: MAGEA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0043066 - negative regulation of apoptotic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 317
+	Hs
		371402 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGA1_HUMAN (1-304): 6.24e-139: 397: 74.34
+	Hs
		372867 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGBA_HUMAN (1-312): 3.77e-132: 381: 41.59
+	Hs
		191509 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGB2_HUMAN (1-315): 4.01e-116: 339: 41.88
+	Hs
		373493 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGD2_HUMAN (13-310): 5.19e-106: 323: 30.10
+	Hs
		373632 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGD1_HUMAN (15-307): 3.9e-92: 291: 30.03
+	Hs
		372945 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		NECD_HUMAN (27-313): 4.91e-93: 280: 27.95
+	Hs
		848933 MAD3_HUMAN (320-450): 1.26e-25: 105: 26.72		MAGAB_HUMAN (1-317): 6.23e-156: 444: 62.19
+	Hs
		191510 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		MAGB2_HUMAN (1-315): 4.01e-116: 339: 41.88