HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MAGD2 (Q9UNF1)
Melanoma-associated antigen D2 (11B6) (Breast cancer-associated gene 1 protein) (BCG-1) (Hepatocellular carcinoma-associated protein JCL-1) (MAGE-D2 antigen)
Gene: MAGED2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 606
+	Hs
		372867 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGBA_HUMAN (251-481): 1.17e-118: 357: 39.83
+	Hs
		373632 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGD1_HUMAN (12-571): 1.47e-111: 353: 36.24
+	Hs
		371403 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGA4_HUMAN (160-474): 2.9e-111: 337: 26.67
+	Hs
		371402 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGA1_HUMAN (162-473): 4.16e-108: 329: 27.24
+	Hs
		191509 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MAGB2_HUMAN (221-485): 5.78e-103: 316: 36.60
+	Hs
		372945 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		NECD_HUMAN (177-494): 7.37e-90: 282: 34.91
+	Hs
		191510 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		MAGB2_HUMAN (221-485): 5.78e-103: 316: 36.60
+	Hs
		848933 MAD3_HUMAN (320-450): 1.26e-25: 105: 26.72		MAGAB_HUMAN (52-484): 3.93e-130: 390: 23.52