HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CPSF2 (Q9P2I0)
Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)
Gene: CPSF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	35013218, 21150319
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 782
+	Hs
		406753 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		CPSF2_HUMAN (1-782): 0: 952: 100.00
+	Hs
		373451 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		CPSF3_HUMAN (2-558): 1.86e-173: 516: 21.28
+	Hs
		372253 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		INT11_HUMAN (5-558): 2.1e-155: 467: 21.67
+	Hs
		406779 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		CPSF3_HUMAN (2-558): 1.86e-173: 516: 21.28