Interactor 1: PUR1 (P04046)
Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase)
Gene: ADE4

Interactor 2: PUR1 (P04046)
Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase)
Gene: ADE4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.852

The method score is based on:

Property Details
Experiments 18467557, 18719252, 22615397
Identification Methods protein complementation assay, two hybrid, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GATase_6~GATase_6, GATase_6~Pribosyltran, Pribosyltran~Pribosyltran
Common GO terms GO:0004044 - amidophosphoribosyltransferase activity
GO:0005737 - cytoplasm
GO:0006164 - purine nucleotide biosynthetic process
GO:0006189 - 'de novo' IMP biosynthetic process
GO:0006541 - glutamine metabolic process
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 510
Sc

1 510
+ Ec
+ Sp
+ Sc
+ Ec
+ Hs
+ Cj
+ Hs
+ Ce
+ Ec
+ Ca

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024