HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: IF4B (P23588)
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene: EIF4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	37045861
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 611
+	Hs
		374212 RAF1_HUMAN (1-648): 0: 652: 100.00		CIRBP_HUMAN (98-257): 1.65e-29: 116: 24.85
+	Hs
		374671 RAF1_HUMAN (1-648): 0: 652: 100.00		MSI2H_HUMAN (82-179): 1.19e-27: 115: 18.37
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22
+	Hs
		201649 RAF1_HUMAN (1-648): 0: 652: 100.00		MSI1H_HUMAN (88-180): 1.42e-23: 104: 22.58
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72
+	Hs
		374678 RAF1_HUMAN (1-648): 0: 652: 100.00		DAZP1_HUMAN (97-186): 2.18e-21: 98.8: 17.78
+	Hs
		374053 RAF1_HUMAN (1-648): 0: 652: 100.00		RBM3_HUMAN (98-241): 2.31e-22: 95.7: 24.83
+	Hs
		488712 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		CIRBP_HUMAN (98-257): 1.65e-29: 116: 24.85
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72
+	Hs
		523106 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MSI2H_HUMAN (82-179): 1.19e-27: 115: 18.37
+	Hs
		433441 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		MSI2H_HUMAN (82-179): 1.19e-27: 115: 18.37
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (54-547): 1.45e-22: 104: 11.07
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72