HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 332
+	Hs
		319043 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24
+	Hs
		319066 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24
+	Hs
		319042 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24
+	Hs
		375213 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		715593 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		215890 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		SYNJ1_HUMAN (8-323): 1.4e-12: 70.6: 12.19
+	Hs
		374421 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		715523 RAB1A_HUMAN (4-187): 2.9e-77: 231: 33.33		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		375784 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		TITIN_HUMAN (3-293): 7.73e-09: 59.5: 13.74
+	Hs
		715521 RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		715510 RAB2A_HUMAN (4-185): 5.47e-74: 223: 31.52		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		976456 RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88		TITIN_HUMAN (3-293): 7.73e-09: 59.5: 13.74
+	Hs
		957983 RAB14_HUMAN (4-185): 1.88e-73: 222: 29.35		TITIN_HUMAN (3-293): 7.73e-09: 59.5: 13.74
+	Hs
		715524 RAP1A_HUMAN (1-165): 1.22e-60: 188: 56.29		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00