HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 332
+	Hs
		319042 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24
+	Hs
		319066 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24
+	Hs
		374421 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		373791 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		319043 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24
+	Hs
		715593 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		715510 RAB2A_HUMAN (4-183): 1.47e-74: 224: 32.97		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		715523 RAB1A_HUMAN (4-187): 3.14e-74: 223: 34.36		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		215890 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		SYNJ1_HUMAN (8-323): 1.4e-12: 70.6: 12.19
+	Hs
		715521 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		715489 RAB13_HUMAN (4-186): 4.35e-72: 218: 36.76		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00
+	Hs
		375784 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		TITIN_HUMAN (3-293): 7.73e-09: 59.5: 13.74
+	Hs
		976456 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		TITIN_HUMAN (3-293): 7.73e-09: 59.5: 13.74
+	Hs
		957983 RAB14_HUMAN (4-184): 2.96e-72: 219: 29.51		TITIN_HUMAN (3-293): 7.73e-09: 59.5: 13.74
+	Hs
		715524 RAP1A_HUMAN (1-165): 7.87e-63: 194: 58.08		MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00