HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37045861
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 648 Hs			1 1382
+	Hs
		373790 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		373884 RAF1_HUMAN (1-648): 0: 652: 100.00		YLPM1_HUMAN (774-1359): 8.27e-43: 174: 21.91
+	Hs
		373791 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH10_HUMAN (46-929): 1.09e-34: 147: 10.53
+	Hs
		375074 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH13_HUMAN (638-1382): 4.53e-29: 128: 8.77
+	Hs
		373794 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH11_HUMAN (79-823): 1.69e-23: 110: 11.10
+	Hs
		374260 RAF1_HUMAN (1-648): 0: 652: 100.00		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Hs
		375162 RAF1_HUMAN (1-648): 0: 652: 100.00		MRCKB_HUMAN (610-1132): 1.14e-14: 82: 10.96
+	Hs
		374446 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH14_HUMAN (488-1381): 1.41e-12: 75.1: 9.26
+	Hs
		373636 RAF1_HUMAN (1-648): 0: 652: 100.00		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		488676 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		MAP1A_HUMAN (494-1117): 2.75e-30: 133: 13.68
+	Hs
		542811 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		488559 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		488765 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		MY18A_HUMAN (532-955): 1.34e-09: 65.3: 16.18
+	Dm
		507767 KRAF1_DROME (45-647): 6.35e-165: 491: 44.98		Q9W179_DROME (592-980): 8.96e-10: 65.7: 16.92
+	Dm
		507730 KRAF1_DROME (45-647): 6.35e-165: 491: 44.98		Q8MLP1_DROME (578-902): 6.87e-09: 63: 17.94
+	Hs
		111443 J3QRU1_HUMAN (329-607): 1.4e-105: 332: 33.92		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		433272 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		412058 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		523231 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MYH4_HUMAN (9-938): 3.72e-23: 109: 9.08
+	Hs
		411983 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18