HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: RBM45 (Q8IUH3)
RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45)
Gene: RBM45

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 476
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (5-411): 7.51e-60: 209: 14.73
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (382-470): 6.62e-13: 72.7: 11.58
+	Hs
		375057 RAF1_HUMAN (1-648): 0: 652: 100.00		PUF60_HUMAN (38-180): 7.95e-12: 69.3: 28.28
+	Hs
		374285 RAF1_HUMAN (1-648): 0: 652: 100.00		ELAV1_HUMAN (5-108): 8.6e-12: 68.2: 24.04
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (5-411): 7.51e-60: 209: 14.73
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (382-470): 6.62e-13: 72.7: 11.58
+	Hs
		488730 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		ELAV1_HUMAN (5-108): 8.6e-12: 68.2: 24.04
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (5-411): 7.51e-60: 209: 14.73
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (382-470): 6.62e-13: 72.7: 11.58
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (382-470): 1.15e-11: 68.9: 11.58
+	Hs
		433366 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		ELAV1_HUMAN (5-108): 8.6e-12: 68.2: 24.04
+	Rn
		1176492 SRC_RAT (331-607): 3.98e-105: 330: 33.10		CELF2_RAT (370-476): 2.6e-10: 64.6: 16.10