Protein: RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)

Gene: RPAB5, POLR2L
Organism: Homo sapiens
Interactions: 159
UniProt ID: P62875

Gene Ontology (top 5):
GO:0001054 - RNA polymerase I activity
GO:0001055 - RNA polymerase II activity
GO:0001056 - RNA polymerase III activity
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

169829

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

5

4

High-throughput

0.927

High

583457

RPB3
DNA-directed RNA polymerase II subunit RPB3

4

4

Small-scale

0.899

High

676857

RPB2
DNA-directed RNA polymerase II subunit RPB2

4

9

Small-scale

0.899

High

921179

RPC2
DNA-directed RNA polymerase III subunit RPC2

4

9

Small-scale

0.892

High

921169

RPA2
DNA-directed RNA polymerase I subunit RPA2

3

9

High-throughput

0.861

High

921177

RPC5
DNA-directed RNA polymerase III subunit RPC5

3

1

High-throughput

0.861

High

179599

RPA34
DNA-directed RNA polymerase I subunit RPA34

2

0

High-throughput

0.748

High

583687

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

5

2

Small-scale

0.723

High

181409

RPB4
DNA-directed RNA polymerase II subunit RPB4

5

1

Small-scale

0.721

High

913889

RPB7
DNA-directed RNA polymerase II subunit RPB7

5

4

Small-scale

0.716

High

854291

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

4

1

Small-scale

0.696

High

317101

RPA1
DNA-directed RNA polymerase I subunit RPA1

4

11

Small-scale

0.694

High

402727

RPC4
DNA-directed RNA polymerase III subunit RPC4

4

1

High-throughput

0.694

High

921172

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

4

3

High-throughput

0.694

High

624853

RPB1
DNA-directed RNA polymerase II subunit RPB1

4

11

Small-scale

0.689

High

921159

RPAP1
RNA polymerase II-associated protein 1

3

1

Small-scale

0.678

High

156014

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

11

High-throughput

0.667

High

854410

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

3

4

High-throughput

0.667

High

897501

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

3

2

High-throughput

0.667

High

921161

RPA49
DNA-directed RNA polymerase I subunit RPA49

3

1

High-throughput

0.667

High

921196

RPC8
DNA-directed RNA polymerase III subunit RPC8

3

4

High-throughput

0.667

High

921180

PIHD1
PIH1 domain-containing protein 1

4

0

High-throughput

0.664

High

921108

REL
Proto-oncogene c-Rel

3

0

High-throughput

0.646

High

48648

MED19
Mediator of RNA polymerase II transcription subunit 19

3

0

High-throughput

0.638

High

313415

MED26
Mediator of RNA polymerase II transcription subunit 26

3

0

High-throughput

0.638

High

123906

SPT5H
Transcription elongation factor SPT5

2

1

High-throughput

0.628

High

921151

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

3

High-throughput

0.628

High

921156

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

2

1

High-throughput

0.628

High

921162

RPC6
DNA-directed RNA polymerase III subunit RPC6

2

1

High-throughput

0.628

High

125340

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

1

High-throughput

0.611

High

270193

RPC9
DNA-directed RNA polymerase III subunit RPC9

2

1

High-throughput

0.611

High

295519

RECQ5
ATP-dependent DNA helicase Q5

2

1

High-throughput

0.611

High

738841

RPB9
DNA-directed RNA polymerase II subunit RPB9

2

5

High-throughput

0.611

High

864937

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

1

High-throughput

0.611

High

921126

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

2

2

High-throughput

0.611

High

921132

SPT6H
Transcription elongation factor SPT6

2

1

High-throughput

0.611

High

921137

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

1

High-throughput

0.611

High

921185

RPA12
DNA-directed RNA polymerase I subunit RPA12

2

6

High-throughput

0.611

High

921195

RPC10
DNA-directed RNA polymerase III subunit RPC10

2

5

High-throughput

0.611

High

921168

GPN2
GPN-loop GTPase 2

3

4

High-throughput

0.609

High

921190

GPN3
GPN-loop GTPase 3

3

4

High-throughput

0.609

High

921154

NACC1
Nucleus accumbens-associated protein 1

2

1

High-throughput

0.606

High

750216

COIL
Coilin

2

0

High-throughput

0.606

High

62136

RCCD1
RCC1 domain-containing protein 1

2

0

High-throughput

0.602

High

638257

RBTN2
Rhombotin-2

2

0

High-throughput

0.602

High

295618

RMP
Unconventional prefoldin RPB5 interactor 1

2

0

High-throughput

0.585

High

921134

SKAP1
Src kinase-associated phosphoprotein 1

2

0

High-throughput

0.585

High

921157

MED10
Mediator of RNA polymerase II transcription subunit 10

2

0

High-throughput

0.585

High

921164

RPAP3
RNA polymerase II-associated protein 3

2

0

High-throughput

0.585

High

921187

UXT
Protein UXT

2

0

High-throughput

0.585

High

246564

MCE1
mRNA-capping enzyme

2

2

High-throughput

0.584

High

893643

PSA6
Proteasome subunit alpha type-6

2

0

High-throughput

0.580

High

921119

PCH2
Pachytene checkpoint protein 2 homolog

2

0

High-throughput

0.580

High

921174

F217B
Protein FAM217B

2

0

High-throughput

0.580

High

921136

PHC2
Polyhomeotic-like protein 2

1

1

High-throughput

0.573

High

921148

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

1

High-throughput

0.573

High

921153

SPAG5
Sperm-associated antigen 5

1

1

High-throughput

0.573

High

244243

BRD4
Bromodomain-containing protein 4

2

0

High-throughput

0.559

High

921163

MED28
Mediator of RNA polymerase II transcription subunit 28

2

0

High-throughput

0.559

High

484444

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

2

4

High-throughput

0.552

High

215885

ZBT14
Zinc finger and BTB domain-containing protein 14

1

0

High-throughput

0.549

High

921114

ASPP2
Apoptosis-stimulating of p53 protein 2

1

0

High-throughput

0.549

High

921139

BANP
Protein BANP

1

0

High-throughput

0.549

High

921178

THAP1
THAP domain-containing protein 1

1

0

High-throughput

0.549

High

921116

GRB7
Growth factor receptor-bound protein 7

2

0

High-throughput

0.547

High

175529

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

1

High-throughput

0.536

High

589821

TBP
TATA-box-binding protein

1

1

High-throughput

0.536

High

839474

SPB8
Serpin B8

1

5

High-throughput

0.536

High

921124

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

1

High-throughput

0.536

High

921158

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.536

High

921160

RPB1B
DNA-directed RNA polymerase II subunit RPB11-b1

1

4

High-throughput

0.536

High

921170

GPN1
GPN-loop GTPase 1

1

4

High-throughput

0.536

High

921192

SPB13
Serpin B13

1

4

High-throughput

0.536

High

921197

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.536

High

473902

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

2

0

High-throughput

0.528

High

331247

CHK2
Serine/threonine-protein kinase Chk2

1

0

High-throughput

0.518

High

921122

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

203905

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

259839

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.513

High

396218

ARGI1
Arginase-1

1

0

High-throughput

0.513

High

446575

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

448603

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

538897

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

726723

FUS
RNA-binding protein FUS

1

0

High-throughput

0.513

High

742193

SYUA
Alpha-synuclein

1

0

High-throughput

0.513

High

787716

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.513

High

854089

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.513

High

911798

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

921107

DSG1
Desmoglein-1

1

0

High-throughput

0.513

High

921115

PKP1
Plakophilin-1

1

0

High-throughput

0.513

High

921129

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.513

High

921131

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

921138

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

921181

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

921182

ASB6
Ankyrin repeat and SOCS box protein 6

1

0

High-throughput

0.513

High

921183

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.513

High

921184

RRN3
RNA polymerase I-specific transcription initiation factor RRN3

1

0

High-throughput

0.513

High

921191

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.513

High

271861

SPB7
Serpin B7

1

5

High-throughput

0.489

High

397021

PAI2
Plasminogen activator inhibitor 2

1

5

High-throughput

0.489

High

921135

SPA12
Serpin A12

1

5

High-throughput

0.489

High

921149

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

921152

SPB12
Serpin B12

1

4

High-throughput

0.489

High

921155

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

225366

MED14
Mediator of RNA polymerase II transcription subunit 14

1

3

High-throughput

0.479

High

346448

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

379239

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

917068

H4
Histone H4

1

1

High-throughput

0.479

High

921109

SUH
Recombining binding protein suppressor of hairless

1

1

High-throughput

0.479

High

921166

SFR19
Splicing factor, arginine/serine-rich 19

1

1

High-throughput

0.479

High

921189

PFD2
Prefoldin subunit 2

1

1

High-throughput

0.479

High

921173

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.460

High

304604

SCAF4
SR-related and CTD-associated factor 4

1

0

High-throughput

0.458

High

322445

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

442028

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

532484

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

569542

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

610334

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

823839

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

877676

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

921111

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

921112

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.458

High

921113

CUL3
Cullin-3

1

0

High-throughput

0.458

High

921117

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

921120

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.458

High

921121

IKBB
NF-kappa-B inhibitor beta

1

0

High-throughput

0.458

High

921123

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.458

High

921128

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.458

High

921130

INT5
Integrator complex subunit 5

1

0

High-throughput

0.458

High

921144

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

921145

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

921146

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.458

High

921147

MED30
Mediator of RNA polymerase II transcription subunit 30

1

0

High-throughput

0.458

High

921165

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

921167

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.458

High

921171

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

921176

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.458

High

921188

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

921193

INT6
Integrator complex subunit 6

1

0

High-throughput

0.458

High

921125

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

921186

PHRF1
PHD and RING finger domain-containing protein 1

1

1

High-throughput

0.437

High

484407

RPC22
Protein POLR1D, isoform 2

1

0

High-throughput

0.426

High

473861

MYZAP
Myocardial zonula adherens protein

1

1

High-throughput

0.407

High

921127

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

4

0

High-throughput

0.353

High

921175

PDRG1
p53 and DNA damage-regulated protein 1

2

0

High-throughput

0.318

High

329610

AGR2
Anterior gradient protein 2 homolog

2

0

High-throughput

0.316

High

921194

SNX7
Sorting nexin-7

1

0

High-throughput

0.282

High

522600

MYH7
Myosin-7

1

0

High-throughput

0.279

Low

921110

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.279

Low

921118

CDSN
Corneodesmosin

1

0

High-throughput

0.279

Low

921140

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

921142

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

921143

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

822712

CCN3
CCN family member 3

1

0

Small-scale

0.251

Low

171602

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.249

Low

887528

ELOF1
Transcription elongation factor 1 homolog

1

0

Small-scale

0.249

Low

921133

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

921141

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

921150

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024