HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: SPY4 (Q9C004)
Protein sprouty homolog 4 (Spry-4)
Gene: SPRY4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	12717443, 38496616
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 299
+	Hs
		208085 RAF1_HUMAN (1-648): 0: 652: 100.00		SPY2_HUMAN (27-291): 9.66e-99: 294: 39.86
+	Hs
		374453 RAF1_HUMAN (1-648): 0: 652: 100.00		SPRE1_HUMAN (97-259): 6.2e-51: 175: 21.30
+	Hs
		208091 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		SPY2_HUMAN (27-291): 9.66e-99: 294: 39.86
+	Hs
		412242 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		SPRE1_HUMAN (97-259): 6.2e-51: 175: 21.30