Interactor 1: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1
Interactor 2: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.60 | 0.501 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10652271 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0045742 - positive regulation of epidermal growth factor receptor signaling pathway |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
