HitPredict

Interactor 1: IFN21 (P01568)
Interferon alpha-21 (IFN-alpha-21) (Interferon alpha-F) (LeIF F)
Gene: IFNA21

Interactor 2: IFIT1 (P09914)
Antiviral innate immune response effector IFIT1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56) (Interferon-induced protein with tetratricopeptide repeats 1)
Gene: IFIT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051607 - defense response to virus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 478
+	Hs
		378313 IFNA5_HUMAN (1-189): 4.49e-104: 298: 86.77		IFIT1_HUMAN (1-478): 2.34e-93: 292: 100.00
+	Hs
		378261 IFN10_HUMAN (1-189): 7.67e-102: 293: 91.01		IFIT1_HUMAN (1-478): 2.34e-93: 292: 100.00
+	Hs
		378325 IFN14_HUMAN (1-189): 1.08e-99: 287: 82.01		IFIT1_HUMAN (1-478): 2.34e-93: 292: 100.00
+	Hs
		378269 IFNA7_HUMAN (1-189): 4.77e-99: 286: 87.83		IFIT1_HUMAN (1-478): 2.34e-93: 292: 100.00
+	Hs
		488154 IFNA8_HUMAN (1-189): 1.02e-94: 275: 81.48		IFIT1_HUMAN (1-478): 2.34e-93: 292: 100.00
+	Hs
		166733 IFNA5_HUMAN (1-189): 4.49e-104: 298: 86.77		IFIT3_HUMAN (217-476): 1.57e-12: 71.4: 12.50
+	Hs
		166732 IFN21_HUMAN (1-189): 3.22e-101: 291: 100.00		IFIT3_HUMAN (217-476): 1.57e-12: 71.4: 12.50
+	Hs
		166734 IFN14_HUMAN (1-189): 1.08e-99: 287: 82.01		IFIT3_HUMAN (217-476): 1.57e-12: 71.4: 12.50
+	Hs
		166731 IFNA7_HUMAN (1-189): 4.77e-99: 286: 87.83		IFIT3_HUMAN (217-476): 1.57e-12: 71.4: 12.50
+	Hs
		166730 IFNA2_HUMAN (1-189): 1.22e-94: 275: 81.48		IFIT3_HUMAN (217-476): 1.57e-12: 71.4: 12.50
+	Hs
		166760 IFNA8_HUMAN (1-189): 1.02e-94: 275: 81.48		IFIT3_HUMAN (217-476): 1.57e-12: 71.4: 12.50