Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C
Interactor 2: KI2L1 (P43626)
Killer cell immunoglobulin-like receptor 2DL1 (CD158 antigen-like family member A) (Natural killer-associated transcript 1) (NKAT-1) (p58 natural killer cell receptor clones CL-42/47.11) (p58 NK receptor CL-42/47.11) (p58.1 MHC class-I-specific NK receptor) (CD antigen CD158a)
Gene: KIR2DL1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11163076, 9768753, 12454284, 11323700, 19858347, 16141329, 12853576, 28546555, 18624290 |
| Identification Methods | pull down, x-ray crystallography, fluorescence polarization spectroscopy, surface plasmon resonance, affinity chromatography technology, fluorescence-activated cell sorting |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1-set~ig, MHC_I~ig |
| Common GO terms | GO:0005886 - plasma membrane GO:0006955 - immune response |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
