HitPredict

Interactor 1: H2B2 (P02294)
Histone H2B.2
Gene: HTB2

Interactor 2: DPOE (P21951)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POL2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	11805826, 23499444, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 2222
+	Sc
		380966 H2B1_YEAST (1-131): 4.06e-44: 142: 96.95		DPOE_YEAST (1-2222): 0: 2941: 100.00
+	Hs
		702918 H2B1C_HUMAN (7-129): 9.05e-47: 148: 70.40		DPOD1_HUMAN (1-637): 3.44e-144: 481: 14.67
+	Hs
		487993 H2B1C_HUMAN (7-129): 9.05e-47: 148: 70.40		DPOLA_HUMAN (89-635): 1.09e-97: 351: 12.42
+	Sc
		381380 H2B2_YEAST (1-131): 1.09e-45: 146: 100.00		DPOLA_YEAST (231-637): 1.78e-77: 287: 10.92
+	Sc
		380938 H2B1_YEAST (1-131): 4.06e-44: 142: 96.95		DPOLA_YEAST (231-637): 1.78e-77: 287: 10.92
+	Hs
		253251 H2B2F_HUMAN (7-129): 8.61e-48: 151: 70.40		REV3L_HUMAN (265-637): 1.89e-71: 269: 11.14