HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: CAF1A (Q12495)
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (CAF-1 90 kDa subunit) (Chromatin assembly factor 1 subunit p90) (RAP1 localization factor 2)
Gene: RLF2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.933

Property	Details
Experiments	14651846, 27690308, 18373695, 22199229, 23034810, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	CAF1A~CENP-T_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0006334 - nucleosome assembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 606
+	Hs
		979583 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		CAF1A_HUMAN (30-476): 5.13e-52: 194: 17.13
+	Mm
		980677 H4_MOUSE (18-103): 1.93e-41: 133: 90.70		CAF1A_MOUSE (52-476): 1.9e-49: 186: 17.16
+	Hs
		302465 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		RNF8_HUMAN (53-284): 1.03e-26: 115: 15.02
+	Sc
		381994 H4_YEAST (1-103): 5.31e-47: 147: 100.00		SEC3_YEAST (62-254): 4.55e-19: 93.9: 17.01
+	Sc
		382402 H4_YEAST (1-103): 5.31e-47: 147: 100.00		MDN1_YEAST (36-506): 7.72e-12: 70.8: 12.19