Protein: CAF1A
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150)

Gene: CAF1A, CHAF1A
Organism: Homo sapiens
Interactions: 172
UniProt ID: Q13111

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006260 - DNA replication
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

998268

H31
Histone H3.1

23

19

Small-scale

0.988

High

1066280

RBBP4
Histone-binding protein RBBP4

8

15

Small-scale

0.967

High

979583

H4
Histone H4

6

8

Small-scale

0.937

High

1016817

H33
Histone H3.3

3

19

Small-scale

0.861

High

1094667

CAF1A
Chromatin assembly factor 1 subunit A

2

15

Small-scale

0.825

High

1094697

H32
Histone H3.2

2

19

Small-scale

0.767

High

853241

CBX5
Chromobox protein homolog 5

9

13

Small-scale

0.755

High

551021

PCNA
Proliferating cell nuclear antigen

8

3

Small-scale

0.754

High

1094742

ASF1B
Histone chaperone ASF1B

7

5

Small-scale

0.747

High

1094668

CAF1B
Chromatin assembly factor 1 subunit B

7

11

Small-scale

0.746

High

1094669

CBX3
Chromobox protein homolog 3

6

13

Small-scale

0.733

High

1014081

CBX1
Chromobox protein homolog 1

4

13

Small-scale

0.704

High

729794

1433B
14-3-3 protein beta/alpha

4

18

Small-scale

0.702

High

971467

1433E
14-3-3 protein epsilon

4

3

High-throughput

0.693

High

1094684

H2B2E
Histone H2B type 2-E

1

9

High-throughput

0.691

High

1094750

MBD1
Methyl-CpG-binding domain protein 1

3

4

Small-scale

0.686

High

1048840

REL
Proto-oncogene c-Rel

3

5

High-throughput

0.675

High

1094753

ASF1A
Histone chaperone ASF1A

3

5

Small-scale

0.660

High

990168

1433Z
14-3-3 protein zeta/delta

3

18

Small-scale

0.658

High

587071

ITF2
Transcription factor 4

3

0

High-throughput

0.646

High

259880

BRD4
Bromodomain-containing protein 4

3

9

Small-scale

0.640

High

591626

H2AX
Histone H2AX

1

5

High-throughput

0.618

High

883526

CENPA
Histone H3-like centromeric protein A

1

19

High-throughput

0.618

High

980734

H2B1C
Histone H2B type 1-C/E/F/G/I

1

9

High-throughput

0.618

High

964256

SUMO2
Small ubiquitin-related modifier 2

2

5

Small-scale

0.614

High

699728

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

7

High-throughput

0.611

High

1094677

SETB1
Histone-lysine N-methyltransferase SETDB1

2

8

Small-scale

0.611

High

70965

NOTO
Homeobox protein notochord

2

2

High-throughput

0.606

High

685181

PAX6
Paired box protein Pax-6

2

3

High-throughput

0.606

High

907268

STA5B
Signal transducer and activator of transcription 5B

2

1

High-throughput

0.606

High

1007914

PO6F2
POU domain, class 6, transcription factor 2

2

4

High-throughput

0.606

High

1094722

TRIB3
Tribbles homolog 3

2

1

High-throughput

0.606

High

674153

BRD2
Bromodomain-containing protein 2

2

13

High-throughput

0.584

High

1094696

ZN620
Zinc finger protein 620

2

0

High-throughput

0.580

High

1094748

SRTD1
SERTA domain-containing protein 1

2

0

High-throughput

0.580

High

132469

CDC7
Cell division cycle 7-related protein kinase

1

7

Small-scale

0.578

High

913312

MSH6
DNA mismatch repair protein Msh6

1

5

Small-scale

0.578

High

926341

BLM
RecQ-like DNA helicase BLM

1

5

Small-scale

0.573

High

1094724

GFI1
Zinc finger protein Gfi-1

1

1

Small-scale

0.573

High

396020

ESR1
Estrogen receptor

2

14

High-throughput

0.571

High

558087

XRCC6
X-ray repair cross-complementing protein 6

1

1

Small-scale

0.561

High

559333

XRCC5
X-ray repair cross-complementing protein 5

1

1

Small-scale

0.561

High

687231

HMGB2
High mobility group protein B2

1

9

Small-scale

0.561

High

813459

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

3

Small-scale

0.561

High

1029277

SET
Protein SET

1

1

Small-scale

0.561

High

1094673

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

5

Small-scale

0.561

High

1094712

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

5

Small-scale

0.561

High

1094751

DDX41
Probable ATP-dependent RNA helicase DDX41

1

1

Small-scale

0.561

High

211311

RFOX2
RNA binding protein fox-1 homolog 2

1

3

High-throughput

0.541

High

966261

1433G
14-3-3 protein gamma

1

18

High-throughput

0.541

High

667818

CDK2
Cyclin-dependent kinase 2

1

5

Small-scale

0.536

High

1065165

SSRP1
FACT complex subunit SSRP1

1

5

High-throughput

0.536

High

1094681

TEAD2
Transcriptional enhancer factor TEF-4

1

1

High-throughput

0.536

High

1094686

TIGD6
Tigger transposable element-derived protein 6

1

2

High-throughput

0.536

High

1094683

H31T
Histone H3.1t

1

19

High-throughput

0.527

High

939184

SUMO3
Small ubiquitin-related modifier 3

1

5

Small-scale

0.527

High

1094749

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.515

High

550255

PABP1
Polyadenylate-binding protein 1

1

3

Small-scale

0.501

High

629111

CCNA2
Cyclin-A2

1

1

Small-scale

0.501

High

690964

1433T
14-3-3 protein theta

1

18

Small-scale

0.501

High

991313

SUMO1
Small ubiquitin-related modifier 1

1

5

Small-scale

0.501

High

1094705

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

3

High-throughput

0.494

High

1094740

ZN408
Zinc finger protein 408

1

0

High-throughput

0.486

High

227534

SPOP
Speckle-type POZ protein

1

2

Small-scale

0.481

High

1094713

CBP
CREB-binding protein

1

7

Small-scale

0.481

High

163755

TCRG1
Transcription elongation regulator 1

1

5

Small-scale

0.479

High

316832

MTA2
Metastasis-associated protein MTA2

1

5

High-throughput

0.479

High

344928

WIZ
Protein Wiz

1

1

High-throughput

0.479

High

352126

MBD3
Methyl-CpG-binding domain protein 3

1

2

High-throughput

0.479

High

371912

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

440527

FYN
Tyrosine-protein kinase Fyn

1

5

High-throughput

0.479

High

519499

MYBB
Myb-related protein B

1

4

High-throughput

0.479

High

593981

NCK1
SH2/SH3 adapter protein NCK1

1

16

High-throughput

0.479

High

695340

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

Small-scale

0.479

High

697097

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

703308

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

18

High-throughput

0.479

High

768078

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

830657

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

879032

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

897453

TOB1
Protein Tob1

1

1

Small-scale

0.479

High

1008120

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

Small-scale

0.479

High

1023228

RBM3
RNA-binding protein 3

1

3

Small-scale

0.479

High

1032933

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

1054695

SUH
Recombining binding protein suppressor of hairless

1

1

High-throughput

0.479

High

1086753

BPTF
Nucleosome-remodeling factor subunit BPTF

1

11

High-throughput

0.479

High

1088308

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

13

High-throughput

0.479

High

1094670

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1094672

TOB2
Protein Tob2

1

1

Small-scale

0.479

High

1094675

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

13

High-throughput

0.479

High

1094678

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1094679

BRD3
Bromodomain-containing protein 3

1

10

High-throughput

0.479

High

1094680

NONO
Non-POU domain-containing octamer-binding protein

1

4

Small-scale

0.479

High

1094682

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.479

High

1094687

ARI4B
AT-rich interactive domain-containing protein 4B

1

7

High-throughput

0.479

High

1094689

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

1

High-throughput

0.479

High

1094692

ADNP2
Activity-dependent neuroprotector homeobox protein 2

1

6

High-throughput

0.479

High

1094701

P66A
Transcriptional repressor p66-alpha

1

2

High-throughput

0.479

High

1094703

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

1094704

CMYA5
Cardiomyopathy-associated protein 5

1

13

High-throughput

0.479

High

1094706

PAF1
RNA polymerase II-associated factor 1 homolog

1

2

Small-scale

0.479

High

1094707

SCAI
Protein SCAI

1

1

High-throughput

0.479

High

1094709

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

1

Small-scale

0.479

High

1094710

P66B
Transcriptional repressor p66-beta

1

2

High-throughput

0.479

High

1094711

DNJC9
DnaJ homolog subfamily C member 9

1

6

High-throughput

0.479

High

1094714

KAT6A
Histone acetyltransferase KAT6A

1

7

High-throughput

0.479

High

1094717

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

7

High-throughput

0.479

High

1094719

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

13

High-throughput

0.479

High

1094720

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

4

Small-scale

0.479

High

1094721

PWP2A
PWWP domain-containing protein 2A

1

5

High-throughput

0.479

High

1094725

MTA3
Metastasis-associated protein MTA3

1

5

High-throughput

0.479

High

1094727

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.479

High

1094728

PCGF6
Polycomb group RING finger protein 6

1

8

High-throughput

0.479

High

1094731

SP130
Histone deacetylase complex subunit SAP130

1

4

High-throughput

0.479

High

1094734

ADNP
Activity-dependent neuroprotector homeobox protein

1

1

High-throughput

0.479

High

1094737

ZN644
Zinc finger protein 644

1

2

High-throughput

0.479

High

1094738

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

1

High-throughput

0.479

High

1094739

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

9

High-throughput

0.479

High

1094741

DMAP1
DNA methyltransferase 1-associated protein 1

1

1

Small-scale

0.479

High

1094743

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1094744

MBD2
Methyl-CpG-binding domain protein 2

1

2

High-throughput

0.479

High

1094745

DBF4A
Protein DBF4 homolog A

1

3

Small-scale

0.479

High

1094746

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1094752

CNOT6
CCR4-NOT transcription complex subunit 6

1

5

Small-scale

0.479

High

1094754

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

155301

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.458

High

282245

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.458

High

658147

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.458

High

860177

RS9
Small ribosomal subunit protein uS4

1

0

Small-scale

0.458

High

978903

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

1005857

GTF2I
General transcription factor II-I

1

0

Small-scale

0.458

High

1032804

XPC
DNA repair protein complementing XP-C cells

1

0

Small-scale

0.458

High

1094676

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1094693

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.458

High

1094698

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.458

High

1094708

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1094716

NSL1
Kinetochore-associated protein NSL1 homolog

1

0

High-throughput

0.458

High

1094730

MIS12
Protein MIS12 homolog

1

0

High-throughput

0.458

High

1094733

BC11A
BCL11 transcription factor A

1

0

High-throughput

0.458

High

1094735

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.458

High

1094736

WNK1
Serine/threonine-protein kinase WNK1

1

5

High-throughput

0.457

High

338834

CBX6
Chromobox protein homolog 6

1

13

High-throughput

0.445

High

344181

PTBP3
Polypyrimidine tract-binding protein 3

1

3

High-throughput

0.445

High

429810

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

105852

APRIO
Alternative prion protein

1

7

High-throughput

0.437

High

157309

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.437

High

190893

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

9

High-throughput

0.437

High

276775

TBCA
Tubulin-specific chaperone A

1

1

High-throughput

0.437

High

619046

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

1

High-throughput

0.437

High

1060512

KLC1
Kinesin light chain 1

1

1

High-throughput

0.437

High

1094671

SQSTM
Sequestosome-1

1

4

Small-scale

0.437

High

1094674

BECN1
Beclin-1

1

3

Small-scale

0.437

High

1094695

BAKOR
Beclin 1-associated autophagy-related key regulator

1

1

Small-scale

0.437

High

1094718

Z512B
Zinc finger protein 512B

1

5

High-throughput

0.437

High

1094723

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

Small-scale

0.437

High

1094747

HMGX4
HMG domain-containing protein 4

1

9

High-throughput

0.437

High

591289

CD44
CD44 antigen

1

2

High-throughput

0.407

High

1094694

S39A5
Zinc transporter ZIP5

1

5

High-throughput

0.407

High

1094699

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.328

High

71510

MEI4
Meiosis-specific protein MEI4

2

0

High-throughput

0.316

High

1094685

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.305

High

1094732

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

0

High-throughput

0.282

High

1012821

RT09
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.269

Low

1048306

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.249

Low

1094688

SGO1
Shugoshin 1

1

0

High-throughput

0.249

Low

1094690

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.249

Low

1094691

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.249

Low

1094700

AROS
Active regulator of SIRT1

1

0

High-throughput

0.249

Low

1094702

BAP18
BPTF-associated chromatin complex component 1

1

0

High-throughput

0.249

Low

1094715

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.249

Low

1094726

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low

1094729

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025