HitPredict

Interactor 1: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1

Interactor 2: TIMP2 (P16035)
Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2)
Gene: TIMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39238192
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002020 - protease binding GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1464 Hs			1 220
+	Hs
		438025 CO5A2_HUMAN (1-1464): 0: 691: 58.00		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		590796 CO5A1_HUMAN (3-654): 7.02e-36: 151: 36.76		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		384279 CO3A1_HUMAN (1-603): 8.13e-28: 124: 37.07		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		384240 CO2A1_HUMAN (3-246): 5.62e-17: 89.5: 27.24		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		370003 CO5A1_HUMAN (3-654): 7.02e-36: 151: 36.76		TIMP1_HUMAN (10-203): 5.84e-86: 255: 42.29
+	Hs
		590890 COGA1_HUMAN (988-1266): 1.3e-11: 71.8: 23.34		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		465933 CO1A2_HUMAN (5-178): 4.39e-09: 63.7: 22.41		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00