HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: TBB6 (Q9BUF5)
Tubulin beta-6 chain (Tubulin beta class V)
Gene: TUBB6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 446
+	Hs
		384794 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBB3_HUMAN (1-446): 0: 727: 92.38
+	Hs
		384107 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBB5_HUMAN (1-429): 0: 719: 92.54
+	Hs
		384633 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBB4B_HUMAN (1-427): 0: 717: 92.74
+	Hs
		385452 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBB2B_HUMAN (1-430): 0: 717: 92.79
+	Hs
		508174 FGFR1_HUMAN (195-794): 0: 545: 26.34		TBB6_HUMAN (1-446): 0: 720: 100.00
+	Hs
		381109 FGFR1_HUMAN (195-794): 0: 545: 26.34		TBB4A_HUMAN (1-427): 0: 713: 93.44
+	Hs
		1081592 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		TBB6_HUMAN (1-446): 0: 720: 100.00
+	Hs
		435747 IGF1R_HUMAN (493-777): 6.97e-71: 255: 42.61		TBB6_HUMAN (1-446): 0: 720: 100.00
+	Hs
		537737 INSRR_HUMAN (493-782): 6.64e-66: 241: 42.91		TBB3_HUMAN (1-446): 0: 727: 92.38
+	Hs
		411272 INSR_HUMAN (493-777): 3e-68: 248: 42.62		TBB5_HUMAN (1-429): 0: 719: 92.54
+	Hs
		968471 ROR2_HUMAN (515-783): 2.79e-66: 239: 43.91		TBB6_HUMAN (1-446): 0: 720: 100.00
+	Hs
		934024 ALK_HUMAN (505-790): 8.72e-63: 231: 42.07		TBB4B_HUMAN (1-427): 0: 717: 92.74