HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.620

Property	Details
Experiments	22365833, 32814053
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043122 - regulation of canonical NF-kappaB signal transduction
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 315
+	Hs
		358877 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		236183 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40
+	Hs
		358724 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Dm
		359260 HSP27_DROME (6-205): 6.07e-44: 147: 30.77		LIS1_DROME (62-312): 8.41e-75: 237: 20.07