Protein: C1QC
Complement C1q subcomponent subunit C

Gene: C1QC
Organism: Homo sapiens
Interactions: 67
UniProt ID: P02747

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005581 - collagen trimer
GO:0005602 - complement component C1 complex
GO:0005615 - extracellular space
GO:0006955 - immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

299856

C1QRF
C1q-related factor

1

19

High-throughput

0.691

High

384226

CO2A1
Collagen alpha-1(II) chain

1

20

High-throughput

0.691

High

388761

CO4A2

1

20

High-throughput

0.691

High

388763

CO6A1

1

20

High-throughput

0.691

High

388764

CO6A2

1

20

High-throughput

0.691

High

388766

CO5A1

1

20

High-throughput

0.691

High

388771

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

20

High-throughput

0.691

High

388777

COEA1
Collagen alpha-1(XIV) chain

1

20

High-throughput

0.691

High

388756

C1QC
Complement C1q subcomponent subunit C

1

20

Small-scale

0.647

High

388595

C1QA
Complement C1q subcomponent subunit A

1

18

Small-scale

0.618

High

388807

UBQL2
Ubiquilin-2

2

11

High-throughput

0.553

High

388806

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

2

1

High-throughput

0.549

High

387188

APOA1
Apolipoprotein A-I

1

1

High-throughput

0.536

High

388769

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.536

High

388773

SERPH
Serpin H1

1

4

High-throughput

0.536

High

388809

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.536

High

388762

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.489

High

388781

DDI2
Protein DDI1 homolog 2

1

11

High-throughput

0.489

High

388784

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

3

High-throughput

0.489

High

388787

BANP
Protein BANP

1

1

High-throughput

0.489

High

388798

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.489

High

388757

FINC
Fibronectin

1

20

Small-scale

0.479

High

388767

PTX3
Pentraxin-related protein PTX3

1

5

Small-scale

0.479

High

388778

RAGE
Advanced glycosylation end product-specific receptor

1

6

Small-scale

0.479

High

388760

ELNE
Neutrophil elastase

1

11

Small-scale

0.457

High

299503

TRIO
Triple functional domain protein

1

2

High-throughput

0.445

High

388758

F13B
Coagulation factor XIII B chain

1

7

Small-scale

0.445

High

388770

GALNS
N-acetylgalactosamine-6-sulfatase

1

4

High-throughput

0.445

High

388775

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

High-throughput

0.445

High

388790

KLK6
Kallikrein-6

1

7

High-throughput

0.445

High

388801

SIL1
Nucleotide exchange factor SIL1

1

5

High-throughput

0.445

High

388804

STRN4
Striatin-4

1

1

High-throughput

0.445

High

105080

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

388808

TRI33
E3 ubiquitin-protein ligase TRIM33

1

2

High-throughput

0.437

High

254721

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

388759

AP2A
Transcription factor AP-2-alpha

1

1

High-throughput

0.417

High

61392

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.407

High

220555

AKA10
A-kinase anchor protein 10, mitochondrial

1

1

High-throughput

0.407

High

296647

AL1L1
Cytosolic 10-formyltetrahydrofolate dehydrogenase

1

4

High-throughput

0.407

High

388768

1433B
14-3-3 protein beta/alpha

1

4

High-throughput

0.407

High

388772

VHL
von Hippel-Lindau disease tumor suppressor

1

8

High-throughput

0.407

High

388779

MA2A1
Alpha-mannosidase 2

1

12

High-throughput

0.407

High

388780

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

1

4

High-throughput

0.407

High

388783

OGFD3
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

1

14

High-throughput

0.407

High

388786

P3H3
Prolyl 3-hydroxylase 3

1

20

High-throughput

0.407

High

388789

DNJA4
DnaJ homolog subfamily A member 4

1

1

High-throughput

0.407

High

388791

PCD16
Protocadherin-16

1

6

High-throughput

0.407

High

388792

METH
Methionine synthase

1

1

High-throughput

0.407

High

388794

TM2D3
TM2 domain-containing protein 3

1

1

High-throughput

0.407

High

388795

PAAF1
Proteasomal ATPase-associated factor 1

1

1

High-throughput

0.407

High

388800

SIK2
Serine/threonine-protein kinase SIK2

1

2

High-throughput

0.407

High

388805

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

4

High-throughput

0.407

High

388785

ZN534
Zinc finger protein 534

2

0

High-throughput

0.316

High

388765

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.279

Low

388788

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

388793

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

388803

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.279

Low

388776

PTPS
6-pyruvoyl tetrahydrobiopterin synthase

1

0

High-throughput

0.238

Low

87295

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low

212920

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.232

Low

388774

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.232

Low

388782

ANR40
Ankyrin repeat domain-containing protein 40

1

0

High-throughput

0.232

Low

388796

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.232

Low

388797

THUM3
tRNA

1

0

High-throughput

0.232

Low

388799

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.232

Low

388802

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025