Protein: C1QA
Complement C1q subcomponent subunit A

Gene: C1QA
Organism: Homo sapiens
Interactions: 106
UniProt ID: P02745

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001774 - microglial cell activation
GO:0005576 - extracellular region
GO:0005581 - collagen trimer
GO:0005602 - complement component C1 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

388594

C1QB
Complement C1q subcomponent subunit B

2

18

Small-scale

0.768

High

388595

C1QC
Complement C1q subcomponent subunit C

1

18

Small-scale

0.618

High

388632

ADIPO
Adiponectin

1

18

Small-scale

0.618

High

388676

UBQL2
Ubiquilin-2

3

9

High-throughput

0.597

High

388610

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

2

Small-scale

0.595

High

388607

PTX3
Pentraxin-related protein PTX3

2

5

Small-scale

0.584

High

388658

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

13

High-throughput

0.553

High

388647

P3H3
Prolyl 3-hydroxylase 3

2

20

High-throughput

0.549

High

137020

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

1

20

High-throughput

0.536

High

249027

NRP2
Neuropilin-2

1

14

High-throughput

0.536

High

251838

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

20

High-throughput

0.536

High

387187

APOA1
Apolipoprotein A-I

1

1

High-throughput

0.536

High

388597

INSR
Insulin receptor

1

8

High-throughput

0.536

High

388608

LYOX
Protein-lysine 6-oxidase

1

3

High-throughput

0.536

High

388611

WNT5A
Protein Wnt-5a

1

12

High-throughput

0.536

High

388620

TBA4A
Tubulin alpha-4A chain

1

1

High-throughput

0.536

High

388631

NPTX1
Neuronal pentraxin-1

1

5

High-throughput

0.536

High

388664

CNTP3
Contactin-associated protein-like 3

1

19

High-throughput

0.536

High

388602

HMGB1
High mobility group protein B1

1

4

Small-scale

0.508

High

388617

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

Small-scale

0.508

High

388672

NLGN3
Neuroligin-3

1

3

Small-scale

0.508

High

388478

CRP

1

5

Small-scale

0.501

High

388596

FINC
Fibronectin

1

20

Small-scale

0.501

High

388600

PGS2
Decorin

1

3

Small-scale

0.501

High

388604

THIO
Thioredoxin

1

2

Small-scale

0.501

High

136582

MANBA
Beta-mannosidase

1

4

High-throughput

0.489

High

269649

PLXA2
Plexin-A2

1

5

High-throughput

0.489

High

388598

ITAV
Integrin alpha-V

1

3

High-throughput

0.489

High

388605

ITA4
Integrin alpha-4

1

3

High-throughput

0.489

High

388606

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

1

High-throughput

0.489

High

388621

RN5A
2-5A-dependent ribonuclease

1

1

High-throughput

0.489

High

388625

TBB3
Tubulin beta-3 chain

1

2

High-throughput

0.489

High

388626

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

3

High-throughput

0.489

High

388634

T132A
Transmembrane protein 132A

1

2

High-throughput

0.489

High

388637

TBB8
Tubulin beta-8 chain

1

2

High-throughput

0.489

High

388638

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

3

High-throughput

0.489

High

388643

SUSD1
Sushi domain-containing protein 1

1

11

High-throughput

0.489

High

388644

EST3
Carboxylesterase 3

1

3

High-throughput

0.489

High

388645

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

3

High-throughput

0.489

High

388648

GT252
Procollagen galactosyltransferase 2

1

20

High-throughput

0.489

High

388651

PGLT1
Protein O-glucosyltransferase 1

1

4

High-throughput

0.489

High

388666

NELFA
Negative elongation factor A

1

5

High-throughput

0.489

High

388673

MRC2
C-type mannose receptor 2

1

20

High-throughput

0.489

High

388674

SE1L1
Protein sel-1 homolog 1

1

15

High-throughput

0.489

High

388679

DD19B
ATP-dependent RNA helicase DDX19B

1

1

High-throughput

0.489

High

366117

C1R
Complement C1r subcomponent

1

10

Small-scale

0.479

High

388603

C1S
Complement C1s subcomponent

1

9

Small-scale

0.479

High

388629

RAGE
Advanced glycosylation end product-specific receptor

1

5

Small-scale

0.479

High

388668

HIPK3
Homeodomain-interacting protein kinase 3

1

2

High-throughput

0.464

High

388619

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

Small-scale

0.458

High

388622

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

0

Small-scale

0.458

High

388601

ELNE
Neutrophil elastase

1

8

Small-scale

0.457

High

366454

UROK
Urokinase-type plasminogen activator

1

3

High-throughput

0.445

High

388599

PROS
Vitamin K-dependent protein S

1

20

High-throughput

0.445

High

388615

INHBE
Inhibin beta E chain

1

11

High-throughput

0.445

High

388616

LOXL3
Lysyl oxidase homolog 3

1

5

High-throughput

0.445

High

388624

DNJC3
DnaJ homolog subfamily C member 3

1

4

High-throughput

0.445

High

388627

GAS6
Growth arrest-specific protein 6

1

14

High-throughput

0.445

High

388656

KLK6
Kallikrein-6

1

4

High-throughput

0.445

High

226660

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

13

High-throughput

0.439

High

388612

BAG6
Large proline-rich protein BAG6

1

11

High-throughput

0.439

High

388670

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

3

Small-scale

0.439

High

388680

UBQL1
Ubiquilin-1

1

9

High-throughput

0.439

High

277240

PITX3
Pituitary homeobox 3

1

1

Small-scale

0.437

High

388618

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

388628

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.437

High

388650

SIM20
Small integral membrane protein 20

1

0

High-throughput

0.426

High

61391

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.407

High

220554

AKA10
A-kinase anchor protein 10, mitochondrial

1

1

High-throughput

0.407

High

388614

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

1

High-throughput

0.407

High

388623

SLFN5
Schlafen family member 5

1

1

High-throughput

0.407

High

388636

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

1

4

High-throughput

0.407

High

388639

WDR81
WD repeat-containing protein 81

1

1

High-throughput

0.407

High

388640

LYPL1
Lysophospholipase-like protein 1

1

1

High-throughput

0.407

High

388646

SLN11
Schlafen family member 11

1

1

High-throughput

0.407

High

388654

TM131
Transmembrane protein 131

1

5

High-throughput

0.407

High

388655

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.407

High

388660

PCD16
Protocadherin-16

1

4

High-throughput

0.407

High

388661

METH
Methionine synthase

1

1

High-throughput

0.407

High

388665

SIL1
Nucleotide exchange factor SIL1

1

3

High-throughput

0.407

High

388671

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

4

High-throughput

0.407

High

388677

LAT2
Large neutral amino acids transporter small subunit 2

1

1

High-throughput

0.407

High

388678

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

5

High-throughput

0.407

High

297730

PIAS2
E3 SUMO-protein ligase PIAS2

1

0

High-throughput

0.282

High

388657

GNA1
Glucosamine 6-phosphate N-acetyltransferase

1

0

High-throughput

0.282

High

184051

ACOX3
Peroxisomal acyl-coenzyme A oxidase 3

1

0

High-throughput

0.279

Low

388613

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

1

0

High-throughput

0.279

Low

388635

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

High-throughput

0.279

Low

388659

TECT2
Tectonic-2

1

0

High-throughput

0.279

Low

388675

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

0

High-throughput

0.279

Low

388633

HSPB2
Heat shock protein beta-2

1

0

High-throughput

0.265

Low

388642

S2547
Solute carrier family 25 member 47

1

0

High-throughput

0.251

Low

170604

CLGN
Calmegin

1

0

High-throughput

0.232

Low

214267

MSI1H
RNA-binding protein Musashi homolog 1

1

0

High-throughput

0.232

Low

388609

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.232

Low

388630

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.232

Low

388641

ACD10
Acyl-CoA dehydrogenase family member 10

1

0

High-throughput

0.232

Low

388649

FAM9B
Protein FAM9B

1

0

High-throughput

0.232

Low

388652

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.232

Low

388653

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

0

High-throughput

0.232

Low

388662

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.232

Low

388663

SEN34
tRNA-splicing endonuclease subunit Sen34

1

0

High-throughput

0.232

Low

388667

CENPH
Centromere protein H

1

0

High-throughput

0.232

Low

388669

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.232

Low

388681

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.232

Low

388682

SQOR
Sulfide:quinone oxidoreductase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025