HitPredict

Interactor 1: ITB2 (P05107)
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)
Gene: ITGB2

Interactor 2: KPCG (P05129)
Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)
Gene: PRKCG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11700305
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 769 Hs			1 697
+	Hs
		396610 ITB2_HUMAN (1-769): 0: 742: 100.00		KPCA_HUMAN (1-683): 0: 725: 70.03
+	Hs
		396604 ITB2_HUMAN (1-769): 0: 742: 100.00		KPCB_HUMAN (1-681): 0: 716: 67.79
+	Hs
		403771 ITB1_HUMAN (5-766): 0: 703: 44.61		KPCA_HUMAN (1-683): 0: 725: 70.03
+	Mm
		222499 ITB3_MOUSE (21-766): 0: 642: 38.65		KPCA_MOUSE (1-683): 0: 716: 69.01
+	Mm
		222513 ITB3_MOUSE (21-766): 0: 642: 38.65		KPCB_MOUSE (1-681): 0: 714: 67.50
+	Hs
		396547 ITB3_HUMAN (22-766): 0: 613: 38.31		KPCB_HUMAN (1-681): 0: 716: 67.79
+	Hs
		403799 ITB1_HUMAN (5-766): 0: 703: 44.61		AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68
+	Hs
		396571 ITB3_HUMAN (22-766): 0: 613: 38.31		AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68
+	Hs
		403889 ITB1_HUMAN (5-766): 0: 703: 44.61		KS6A2_HUMAN (247-664): 7.56e-90: 297: 22.94
+	Hs
		396626 ITB2_HUMAN (1-769): 0: 742: 100.00		KPCD_HUMAN (3-166): 8.84e-63: 223: 38.60
+	Hs
		396624 ITB2_HUMAN (1-769): 0: 742: 100.00		KPCE_HUMAN (3-262): 3.13e-57: 209: 34.07
+	Dm
		246711 TENM_DROME (613-720): 2.96e-11: 69.7: 13.49		KPC1_DROME (2-683): 0: 690: 60.84
+	Dm
		246850 TENM_DROME (613-720): 2.96e-11: 69.7: 13.49		AKT1_DROME (242-675): 6.37e-151: 453: 38.22
+	Dm
		247257 TENM_DROME (613-720): 2.96e-11: 69.7: 13.49		Q9VYN1_DROME (348-678): 7.01e-103: 347: 56.33