HitPredict

Interactor 1: LEG2 (P05162)
Galectin-2 (Gal-2) (Beta-galactoside-binding lectin L-14-II) (HL14) (Lactose-binding lectin 2) (S-Lac lectin 2)
Gene: LGALS2

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15356130
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043065 - positive regulation of apoptotic process GO:0098609 - cell-cell adhesion
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 132 Hs			1 798
+	Hs
		403745 LEG1_HUMAN (1-130): 1.97e-51: 161: 42.54		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403775 LEG3_HUMAN (9-131): 7.94e-48: 155: 29.01		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		119084 LEG9_HUMAN (12-129): 3.58e-41: 141: 24.79		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		121077 LEG8_HUMAN (9-128): 1.55e-35: 125: 27.64		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		449183 LEG1_HUMAN (1-130): 1.97e-51: 161: 42.54		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		556408 LEG3_HUMAN (9-131): 7.94e-48: 155: 29.01		ITB4_HUMAN (11-727): 0: 566: 33.65
+	Hs
		449369 LEG1_HUMAN (1-130): 1.97e-51: 161: 42.54		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		449244 LEG1_HUMAN (1-130): 1.97e-51: 161: 42.54		NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26
+	Hs
		449220 LEG1_HUMAN (1-130): 1.97e-51: 161: 42.54		NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80
+	Hs
		50511 PPL13_HUMAN (10-132): 2.3e-40: 133: 18.61		A1L306_HUMAN (375-501): 6.8e-14: 78.2: 20.74
+	Hs
		1253493 PPL13_HUMAN (10-132): 2.3e-40: 133: 18.61		TENR_HUMAN (591-726): 1.07e-13: 77.4: 16.46
+	Hs
		880584 LEG4_HUMAN (12-130): 2.07e-36: 128: 28.69		TEN4_HUMAN (356-480): 1.24e-09: 64.4: 9.22