HitPredict

Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: ITA9 (Q13797)
Integrin alpha-9 (Integrin alpha-RLC)
Gene: ITGA9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 8245132, 28514442, 18230652, 33961781
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_2~Integrin_alpha2, I-EGF_1~Integrin_alpha2, Integrin_B_tail~Integrin_alpha2, FG-GAP~Integrin_beta, Integrin_alpha2~Integrin_beta, Integrin_alpha2~PSI_integrin
Common GO terms GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007160 - cell-matrix adhesion
GO:0007229 - integrin-mediated signaling pathway
and 7 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 798
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024