Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: LRP2 (P98164)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 35384245
Identification Methods affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_CA~fn3
Common GO terms GO:0005764 - lysosome
GO:0005886 - plasma membrane
GO:0006898 - receptor-mediated endocytosis
GO:0008584 - male gonad development
GO:0009897 - external side of plasma membrane
and 8 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1382
Hs

1 4655
+ Rn
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024