HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: FKBP3 (Q00688)
Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase)
Gene: FKBP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FKBP_C~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 224
+	Hs
		411766 NTRK1_HUMAN (1-796): 0: 624: 100.00		FKBP4_HUMAN (74-224): 6.76e-17: 80.5: 24.68
+	Hs
		411877 NTRK1_HUMAN (1-796): 0: 624: 100.00		FKBP5_HUMAN (76-224): 5.64e-14: 72.1: 23.03
+	Rn
		108133 INSR_RAT (493-777): 7.34e-66: 241: 41.95		G3V6L9_RAT (1-224): 5.29e-100: 291: 95.09
+	Hs
		1038632 DDR2_HUMAN (499-781): 3.38e-72: 254: 44.55		FKBP4_HUMAN (74-224): 6.76e-17: 80.5: 24.68
+	Hs
		572921 INSRR_HUMAN (493-782): 6.66e-66: 241: 42.91		FKBP5_HUMAN (76-224): 5.64e-14: 72.1: 23.03
+	At
		1444447 BRL2_ARATH (140-424): 4.86e-17: 88.2: 9.55		FK201_ARATH (130-221): 1.1e-14: 71.2: 47.31
+	Hs
		179607 MUSK_HUMAN (171-374): 3.43e-13: 75.5: 19.07		FKBP5_HUMAN (76-224): 5.64e-14: 72.1: 23.03